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ESTUDO DO LORMETAZEPAM COMO HIPNOINDUTOR
(1983-12-01)
Repeated administration of caffeine induces either sensitization or tolerance of locomotor stimulation depending on the environmental context
(Polish Acad Sciences Inst Pharmacology, 2012-01-01)
Caffeine is the psychostimulant substance consumed in greatest quantities in the world. The repeated administration of psychostimulants can either decrease or increase the drug effect, inducing tolerance or sensitization, ...
Antinociceptive effects of morphine, fentanyl, tramadol and their combination, in morphine-tolerant mice
(Elsevier Inc., 2010)
The development of morphine-tolerance after chronic administration, reduces analgesic efficacy and is a significant clinical problem in some patients; may be managed clinically by increasing the doses of morphine and/or ...
Morfina nasal: Avaliacao da analgesia e dos efeitos colaterais no tratamento da dor pos-operatoria em criancas
(2000-01-01)
Background and Objectives - Postoperative pain is one of the major discomforts but often under treated, especially in the pediatric patient. The aim of this study was to evaluate nasal morphine postoperative analgesia as ...
Estudo clínico randomizado, aberto e comparativo para avaliação de segurança, tolerabilidade e eficácia analgésica de duas diferentes apresentações de medicamento tópico na realização de curetagem dermatológica de molusco contagioso em pacientes pediátricos
(2010-06-01)
Aim: This study aimed to compare the safety and analgesic efficacy of a new topical drug (in two different presentations: cream and aerosol) consisting of benzocaine, menthol and triclosan, in the curettage of molluscum ...
Preventing the recovery of extinguished ethanol tolerance
(ELSEVIER SCIENCE BV., 2016)
There is substantial evidence that drug-paired cues become associated with drug effects. From a Pavlovian perspective, these cues act as conditioned stimuli and elicit conditioned compensatory responses that contribute to ...
Current Status of Allograft Tolerance in Intestinal Transplantation
(Taylor & Francis, 2014-05)
Solid organ transplantation has become a clinical practice after the development of different immunosuppressive drugs that allowed controlling rejection. The price to be paid for that is the permanent risk of infections ...
Repeated administration of caffeine induces either sensitization or tolerance of locomotor stimulation depending on the environmental context
(2012-01-01)
Caffeine is the psychostimulant substance consumed in greatest quantities in the world. The repeated administration of psychostimulants can either decrease or increase the drug effect, inducing tolerance or sensitization, ...