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Molecular characterization of a clinical Haemophilus parainfluenzae isolate with cefotaxime resistance and decreased susceptibility to fluoroquinolones
(Elsevier Science, 2016-10)
We report an H. parainfluenzae clinical isolate resistant to cefotaxime and with decreased susceptibility to ciprofloxacinrecovered from a patient with cystic fibrosis. The isolate had elevated MICs of ampicillin (256 ...
Molecular epidemiology of cefotaxime-resistant but ceftazidime-susceptible Enterobacterales and evaluation of the in vitro bactericidal activity of ceftazidime and cefepime
(Sociedade Brasileira de Microbiologia, 2021-07)
Extended-spectrum β-lactamases (ESBL) production is the main resistance mechanism to third generation cephalosporins (TGCs) in gram-negative bacilli. In Argentina, there is a high prevalence of cefotaximase-type ESBLs ...
Defining substrate specificity in the ctx-m family: The role of asp240 in ceftazidime hydrolysis
(American Society for Microbiology, 2018-06)
The natural diversification of CTX-M -lactamases led to the emergence of Asp240Gly variants in the clinic that confer reduced susceptibility to ceftazidime (CAZ). In this study, we compared the impact of this substitution ...
Biochemical and Molecular Characterization of Three New Variants of AmpC β-Lactamases from Morganella morganii
(American Society for Microbiology, 2006-03)
Morganella morganii produces an inducible, chromosomally encoded AmpC beta-lactamase. We describe in this study three new variants of AmpC within this species with apparent pIs of 6.6 (M19 from M. morganii strain PP19), ...
Throat carriage rate and antimicrobial resistance of streptococcus pyogenes in rural children in Argentina
(Korean Society for Preventive Medicine, 2017-03)
Objectives: The aim of this study was to determine the prevalence of asymptomatic carriers of group A β-hemolytic streptococci (GAS) in children living in a rural community and to investigate the association between episodes ...
Antimicrobial Resistance of Uropathogenic Escherichia coli from Elderly Patients at a General Hospital, Argentina
(Bentham Open, 2018-07)
Background:Urinary Tract Infection (UTI) is a common cause of morbidity and mortality in older adults.Objective:To investigate antimicrobial resistance of uropathogenic Escherichia coli from elderly patients in a General ...
Antibacterial activity of plant extracts from northwestern Argentina
(Wiley Blackwell Publishing, Inc, 2007-06)
To determine the antibacterial and cytotoxic activities of aqueous and ethanolic extracts of northwestern Argentinian plants used in folk medicine. To compare the mentioned activities with those of five commercial antibiotics. ...
Comparative Kinetic Analysis of OXA-438 with Related OXA-48-Type Carbapenem-Hydrolyzing Class D β-Lactamases
(American Chemical Society, 2020-11)
Novel variants of OXA-48-type enzymes with the ability to hydrolyze oxyimino-cephalosporins and carbapenems are increasingly reported. Since its first report in 2011, OXA-163 is now extensively spread throughout Argentina, ...
All Detectable High-Molecular-Mass Penicillin-Binding Proteins Are Modified in a High-Level β-Lactam-Resistant Clinical Isolate of Streptococcus mitis
(American Society for Microbiology, 2001-07)
All detectable high-molecular-mass penicillin-binding proteins (HMM PBPs) are altered in a clinical isolate of Streptococcus mitis for which the b-lactam MICs are increased from those previously reported in our region ...
Low-Molecular-Mass Penicillin Binding Protein 6b (DacD) Is Required for Efficient GOB-18 Metallo--Lactamase Biogenesis in Salmonella enterica and Escherichia coli
(American Society For Microbiology, 2014-01)
Metallo--lactamases (MBLs) are Zn2-containing secretory enzymes of clinical relevance, whose final folding and metal ion assembly steps in Gram-negative bacteria occur after secretion of the apo form to the periplasmic ...