dc.creatorGuillermo Cruz, Javier Acosta
dc.creatorDel Arco, Jon
dc.creatorClemente-Suárez, Vicente Javier
dc.creatorDeroncele, Víctor
dc.creatorFernández-Lucas, Jesús
dc.date2022-08-22T20:35:47Z
dc.date2023-04-28
dc.date2022-08-22T20:35:47Z
dc.date2021-04-28
dc.date.accessioned2023-10-03T19:53:20Z
dc.date.available2023-10-03T19:53:20Z
dc.identifier1867-3880
dc.identifierhttps://hdl.handle.net/11323/9462
dc.identifierhttps://doi.org/10.1002/cctc.202200140
dc.identifier10.1002/cctc.202200140
dc.identifier1867-3899
dc.identifierCorporación Universidad de la Costa
dc.identifierREDICUC - Repositorio CUC
dc.identifierhttps://repositorio.cuc.edu.co/
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9173018
dc.descriptionMolnupiravir (Lagevrio®) is an orally-administered anti-COVID-19 agent. Due to the urgency to meet the worldwide demand and the growing environmental concern, there is a need for speed in the industrial implementation of novel and efficient bioprocesses for Molnupiravir synthesis. This concept paper aims to review the most relevant milestones that have guided important developments in the enzyme-mediated synthesis of Molnupiravir, including detailed comments on the advantages and drawbacks of the different synthetic routes. Finally, based on a personal perspective, new greener processes for Molnupiravir manufacturing are proposed and discussed.
dc.format1 página
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherWiley - VCH Verlag GmbH & CO. KGaA
dc.publisherGermany
dc.relationChemCatChem
dc.relation13
dc.relation14
dc.rights© 1999-2022 John Wiley & Sons, Inc. All rights reserved
dc.rightsAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.rightshttp://purl.org/coar/access_right/c_f1cf
dc.sourcehttps://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cctc.202200140
dc.subject(Chemo) enzymatic processes
dc.subjectEco-friendly
dc.subjectIndustrial scale-up
dc.subjectMolnupiravir
dc.titleEnzyme-mediated synthesis of Molnupiravir: paving the way for the application of biocatalysis in pharmaceutical industry
dc.typeArtículo de revista
dc.typehttp://purl.org/coar/resource_type/c_6501
dc.typeText
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/redcol/resource_type/ART
dc.typeinfo:eu-repo/semantics/draft
dc.typehttp://purl.org/coar/version/c_ab4af688f83e57aa


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