In vitro antimicrobial efficiency of a mouthwash containing triclosan/gantrez and sodium bicarbonate

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorPires, Juliana Rico
dc.creatorRossa Júnior, Carlos
dc.creatorPizzolitto, Antonio Carlos
dc.date2014-05-27T11:22:45Z
dc.date2016-10-25T18:25:04Z
dc.date2014-05-27T11:22:45Z
dc.date2016-10-25T18:25:04Z
dc.date2007-12-31
dc.date.accessioned2017-04-06T01:29:25Z
dc.date.available2017-04-06T01:29:25Z
dc.identifierBrazilian Oral Research, v. 21, n. 4, p. 342-347, 2007.
dc.identifier1806-8324
dc.identifier1807-3107
dc.identifierhttp://hdl.handle.net/11449/70224
dc.identifierhttp://acervodigital.unesp.br/handle/11449/70224
dc.identifier10.1590/S1806-83242007000400011
dc.identifierS1806-83242007000400011
dc.identifier2-s2.0-37349022476.pdf
dc.identifier2-s2.0-37349022476
dc.identifierhttp://dx.doi.org/10.1590/S1806-83242007000400011
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/891365
dc.descriptionSeveral antiseptic substances have been used as adjuncts to routine mechanical procedures of oral hygiene, based on their antimicrobial effects. The objective of this study was to assess in vitro the antimicrobial efficiency of 2 mouthwash containing Triclosan/Gantrez and sodium bicarbonate in comparison to both positive and negative controls. Standard strain samples of Escherichia coli, Pseudomonas aeruginosa, Actinomyces viscosus and Bacillus subtilis were used. Samples of Streptococcus mutans and Gram-negative bacilli were collected from 20 volunteers (10 with a clinically healthy periodontium and 10 presenting biofilm-associated gingivitis). Evaluation of the antimicrobial activity was performed by determining the minimal inhibitory concentration (MIC). The results indicated that the test solution inhibited the growth of both Gram-negative and Gram-positive microorganisms from the volunteers' saliva as well as that of the standard strains at the MIC dilution of 1:20, whereas the MIC dilution of 0.12% chlorhexidine against the same bacteria was 1:80. Thus, even though the tested mouthrinse solution presented an in-vitro antimicrobial activity superior to that of a placebo, it was inferior to that of chlorhexidine.
dc.languageeng
dc.relationBrazilian Oral Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAnti-bacterial agents
dc.subjectIn vitro
dc.subjectTriclosan
dc.subjectbicarbonate
dc.subjectchlorhexidine
dc.subjectmaleic acid derivative
dc.subjectplacebo
dc.subjectpolyvinyl derivative
dc.subjectpolyvinylmethoxyethylene maleic anhydride copolymer
dc.subjectpolyvinylmethoxyethylene-maleic anhydride copolymer
dc.subjecttissue adhesive
dc.subjecttopical antiinfective agent
dc.subjecttriclosan
dc.subjectunclassified drug
dc.subjectadult
dc.subjectdrug effect
dc.subjectfemale
dc.subjectGram negative bacterium
dc.subjectGram positive bacterium
dc.subjecthuman
dc.subjectmale
dc.subjectmouthwash
dc.subjectAdult
dc.subjectAnti-Infective Agents, Local
dc.subjectChlorhexidine
dc.subjectFemale
dc.subjectGram-Negative Bacteria
dc.subjectGram-Positive Bacteria
dc.subjectHumans
dc.subjectMale
dc.subjectMaleates
dc.subjectMouthwashes
dc.subjectPlacebos
dc.subjectPolyvinyls
dc.subjectSodium Bicarbonate
dc.subjectTissue Adhesives
dc.titleIn vitro antimicrobial efficiency of a mouthwash containing triclosan/gantrez and sodium bicarbonate
dc.typeOtro


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