Antisperm antibodies in infertile men and their correlation with seminal parameters

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorGarcia, Patricia C.
dc.creatorRubio, Eliana M.
dc.creatorPereira, Oduvaldo Cämara Marques
dc.date2014-05-27T11:22:25Z
dc.date2016-10-25T18:23:36Z
dc.date2014-05-27T11:22:25Z
dc.date2016-10-25T18:23:36Z
dc.date2007-03-01
dc.date.accessioned2017-04-06T01:23:53Z
dc.date.available2017-04-06T01:23:53Z
dc.identifierReproductive Medicine and Biology, v. 6, n. 1, p. 33-38, 2007.
dc.identifier1445-5781
dc.identifier1447-0578
dc.identifierhttp://hdl.handle.net/11449/69539
dc.identifierhttp://acervodigital.unesp.br/handle/11449/69539
dc.identifier10.1111/j.1447-0578.2007.00162.x
dc.identifier2-s2.0-33846983558
dc.identifierhttp://dx.doi.org/10.1111/j.1447-0578.2007.00162.x
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/890769
dc.descriptionAim: Antisperm antibodies (ASA) in males cause the autoimmune disease 'immune infertility'. The present study intended to detect the presence of ASA and their incidence in men with unexplained infertility, as well as to evaluate the correlation between the presence of ASA and semen parameter alterations. Methods: Blood and sperm assessment were collected to carry out a direct and indirect mixed antiglobulin reaction (MAR) test and semen analysis in infertile and fertile men from the University Hospital of the Faculty of Medicine, Sao Paulo State University, Sao Paulo. Results: In the MARtest, 18.18% of infertile men were positive for ASA. In fertile men, no positivity was found. A significant correlation between the presence of ASA with an increased white blood cell count plus a decreased hypoosmotic swelling test result was observed. Conclusions: The results indicate that ASA are involved in reduced fertility. It is not ASA detection per.se that provides conclusive information about the occurrence of damage to fertility. The correlation between infertility and altered seminal parameters reinforce the ASA participation in this pathology. © 2007 The Authors Journal compilation. © 2007 Japan Society for Reproductive Medicine.
dc.languageeng
dc.relationReproductive Medicine and Biology
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntisperm antibody
dc.subjectInfertility
dc.subjectMan
dc.subjectSemen
dc.subjectSeminal parameters
dc.subjectimmunoglobulin antibody
dc.subjectsperm antibody
dc.subjectadult
dc.subjectantibody detection
dc.subjectblood analysis
dc.subjectBrazil
dc.subjectcontrolled study
dc.subjectcorrelation analysis
dc.subjecthuman
dc.subjecthuman cell
dc.subjectincidence
dc.subjectleukocyte count
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmale infertility
dc.subjectosmosis
dc.subjectpathophysiology
dc.subjectpriority journal
dc.subjectsemen analysis
dc.subjectspermatozoon count
dc.subjectspermatozoon motility
dc.titleAntisperm antibodies in infertile men and their correlation with seminal parameters
dc.typeOtro


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