Article
Alteration in the endogenous intestinal flora of swiss webster mice by experimental Angiostrongylus costaricensis infection
Registro en:
NOBRE, Vandack et al. Alteration in the endogenous intestinal flora of swiss webster mice by experimental Angiostrongylus costaricensis infection. Memórias do Instituto Oswaldo Cruz. v. 99, n.7, p. 717-720, 2004.
0074-0276
10.1590/S0074-02762004000700009
Autor
Nobre, Vandack
Serufo, José Carlos
Carvalho, Omar dos Santos
Mendonça, Cristiane Lafetá Furtado de
Santos, Simone Gonçalves
Mota, Ester Maria
Gomes, Daniel
Braga, Emanuella
Antunes, Carlos Maurício Figueiredo
Lenzi, Henrique Leonel
Lambertucci, José Roberto
Resumen
The association between worm infections and bacterial diseases has only recently been emphasized. This study examined the effect of experimental Angiostrongylus costaricensis infection on endogenous intestinal flora of Swiss Webster mice. Eight mice aging six weeks were selected for this experiment. Four were infected with A. costaricensis and the other four were used as controls. Twenty eight days after the worm infection, all mice in both groups were sacrificed and samples of the contents of the ileum and colon were obtained and cultured for aerobic and anaerobic bacteria. In the mice infected with A. costaricensis there was a significant increase in the number of bacteria of the endogenous intestinal flora, accompanied by a decrease in the number of Peptostreptococcus spp. This alteration in the intestinal flora of mice infected by the nematode may help to understand some bacterial infections described in humans.