Convergence of two major pathophysiologic mechanisms in nasal polyposis: immune response to Staphylococcus aureus and airway remodeling

dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.contributorUniv Ghent
dc.contributorMil Police Hosp
dc.contributorUniversidade de São Paulo (USP)
dc.creatorPezato, Rogerio [UNIFESP]
dc.creatorBalsalobre, Leonardo [UNIFESP]
dc.creatorLima, Milena
dc.creatorBezerra, Thiago F. P.
dc.creatorVoegels, Richard L.
dc.creatorGregório, Luis Carlos [UNIFESP]
dc.creatorStamm, Aldo Cassol [UNIFESP]
dc.creatorvan Zele, Thibaut
dc.date.accessioned2016-01-24T14:31:27Z
dc.date.accessioned2023-09-04T18:50:08Z
dc.date.available2016-01-24T14:31:27Z
dc.date.available2023-09-04T18:50:08Z
dc.date.created2016-01-24T14:31:27Z
dc.date.issued2013-03-28
dc.identifierJournal of Otolaryngology-head & Neck Surgery. London: Biomed Central Ltd, v. 42, 5 p., 2013.
dc.identifier1916-0216
dc.identifierhttp://repositorio.unifesp.br/handle/11600/36104
dc.identifierWOS000318410000002.pdf
dc.identifier10.1186/1916-0216-42-27
dc.identifierWOS:000318410000002
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8619603
dc.description.abstractThis review is addressed two pathophysiologic mechanisms implicated in the pathogenesis of nasal polyposis: the unique remodeling process found in nasal polyp tissue and the immune response of patients with nasal polyposis to Staphylococcus aureus.These two theories converge to the same direction in different aspects, including decreased extracellular matrix production, impaired T regulation and favoring of a Th2 immune response.In patients with nasal polyposis, an exaggerated immune response to Staphylococcus aureus may aggravate the airway remodeling process.
dc.languageeng
dc.publisherBiomed Central Ltd
dc.relationJournal of Otolaryngology-head & Neck Surgery
dc.rightsAcesso aberto
dc.subjectAirway remodeling
dc.subjectSuperantigens
dc.subjectNasal polyps
dc.titleConvergence of two major pathophysiologic mechanisms in nasal polyposis: immune response to Staphylococcus aureus and airway remodeling
dc.typeResenha


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