info:eu-repo/semantics/article
Prevalence of Antimicrobial Resistance in Bacterial Isolates from Dogs and Cats in a Veterinary Diagnostic Laboratory in Colombia from 2016–2019
Registro en:
10.3390/vetsci7040173
2306-7381
Autor
Gómez Beltrán, David Alberto
Villar Argaiz, David
López Osorio, Sara
Ferguson, Duncan C.
Monsalve, Laura K.
Chaparro Gutiérrez, Jenny Jovana
Institución
Resumen
ABSTRACT: The susceptibility to antimicrobials of bacterial isolates from dogs (n = 1256) and
cats (n = 94) was retrospectively evaluated in a veterinary diagnostic laboratory over a 4-year
period (2016–2019). Out of 1316 isolates in dogs, 771 were Staphylococcus spp. distributed as
follows: Staph. pseudointermedius (n = 406), Staph. intermedius (n = 160), Staph. aureus (n = 104),
and Staph. coagulase-negative (n = 101). In common, all Staphylococcus spp. showed a high
prevalence (20–50%) of resistance to ampicillin, cephalosporin, enrofloxacin, gentamicin, tetracycline,
and trimethoprim-sulfonamide, but a low prevalence (1–10%) of resistance to amoxicillin-clavulanate.
With regards to the other families of bacteria, the number of antimicrobials for which resistance
was high (>20%) in dogs was: Enterobacteriaceae (7/12), Enterococcus spp. (10/16), E. coli (11/15),
Pseudomonas spp. (10/13), and Streptococcus spp. (4/9). For urinary tract infections caused by E. coli
or Enterobacteriaceae (Klebsiella spp., Proteus spp.), amikacin and florfenicol were the only drugs that
demonstrated 100% in vitro e cacy. Multi-drug resistance was observed in 18.7% (246/1316) and 22%
(21/97) of the isolates from dogs and cats, respectively. Except for Pseudomonas spp., known for intrinsic
resistance, resistance in other bacteria was likely attributed to high selection pressure. In conclusion,
empirical antimicrobial use cannot be recommended to treat most common infections, and selection
should be based on results from susceptibility testing. COL0153246