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Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score
(2015-09-15)
For more than 100 years, antivenoms have been produced by traditional methods of immunization of large mammals with mixtures of snake venoms (World Health Organization, 2010 and Gutiérrez et al., 2011). With the introduction ...
Identification and Functional Characterization of CLCN1 Mutations Found in Nondystrophic Myotonia Patients
(2016)
Mutations in the gene coding for the skeletal muscle Cl− channel (CLCN1) lead to dominant or recessive myotonia. Here, we identified and characterized CLCN1 mutations in Costa Rican patients, who had been clinically diagnosed ...
El software libre: Una alternativa para automatizar unidades de información
(Bibliotecas, vol. 29, no. 1, 2011, 2011-01-01)
El documento describe la problemática presupuestaria en las
unidades de información y los altos costos del software comercial
especializado en la automatización de bibliotecas. Describe los orígenes del
software libre ...
First record of the sea anemone Bunodosoma californicum (Cnidaria: Actiniaria) on the Pacific coast of Costa Rica
(2015-05)
We report the first record of the sea anemone Bunodosoma californicum on the Pacific coast of Costa Rica, extending its southern distribution. Four specimens were collected from an artificial breakwater in Mata de Limón, ...
Características cineantropométricas e ingesta nutricional de mujeres y hombres costarricenses dedicados al modelaje publicitario
(2016)
El propósito del estudio fue describir las características cineantropométricas y la ingesta nutricional de mujeres y hombres costarricenses dedicados al modelaje publicitario. Se realizó un estudio transversal descriptivo ...
Balanced dynamics of deep and shallow Hadley circulations in the tropics
(Journal of Advances in Modeling Earth Systems 6(3): 777-804, 2014-05-06)
This paper examines the dynamics of large-scale overturning circulations in the tropical atmosphere using an idealized zonally symmetric model on the equatorial b-plane. Under certain simplifications of its coefficients, ...
Identification of phenolic compounds in soursop (Annona muricata) pulp by high-performance liquid chromatography with diode array and electrospray ionization mass spectrometric detection
(2014-11)
Soursop (Annona muricata L., Annonaceae) is a neotropical fruit species producing large fruits that can be consumed fresh and mainly processed. While the leaves, roots and stems of this species have been the subject of ...
Toxicity of Bothrops sp snake venoms from Ecuador and preclinical assessment of the neutralizing efficacy of a polyspecific antivenom from Costa Rica
(2014-09-15)
The toxicological profile of the venoms of the snakes Bothrops asper and Bothrops atrox from Ecuador was investigated, together with the venom of a population of B. asper formerly classified as ‘Bothrops xanthogrammus’. ...
Stratifications on the Moduli Space of Higgs Bundles
(2016-11-02)
The moduli space of Higgs bundles has two stratifications. The Bia lynickiBirula stratification comes from the action of the non-zero complex numbers by multiplication on the Higgs field, and the Shatz stratification arises ...