Artículos de revistas
7-week aerobic exercise training reduces adipocyte area and improves insulin sensitivity in Wistar rats fed a highly palatable diet
Fecha
2016-01-01Registro en:
Motriz. Revista de Educacao Fisica, v. 22, n. 1, p. 12-17, 2016.
1980-6574
1415-9805
10.5016/motriz.v22i1.9271
2-s2.0-84960965025
Autor
Universidade Estadual Paulista (UNESP)
Universidade São Francisco
Universidade de São Paulo (USP)
Institución
Resumen
The aim of this study was to evaluate the effect aerobic exercise training on fat pad mass, adipocyte size, leptin release and insulin sensitivity in rats fed with high fat-palatable diet. Twenty-four male Wistar rats (250-260g) were divided into four groups: sedentary control (CTR/SD), trained control (CTR/TR), obese sedentary (OB/SD) and obese trained (OB/TR). Obese groups were fed with high fat-palatable diet (27% of fat) and control groups fed with AIN-93. Our results showed that aerobic exercise training was effective to reduce body weight and epididymal fat mass in CTR/TR and OB/TR. Insulin and glucose levels were increased in OB/TR compared with OB/SD. Aerobic exercise training reduced the average area of adipocytes in CTR/TR and OB/TR and it was associated with reduced plasma insulin and leptin. In conclusion, 7-week aerobic exercise training reduces adipocyte area and improves insulin sensitivity and leptin levels in high fat-palatable diet-fed Wistar rats.