info:eu-repo/semantics/article
Structural factors of annonaceous acetogenins and their semisynthetic analogues related with the toxicity on Spodoptera frugiperda
Fecha
2015-06Registro en:
Di Toto Blessing, Lilian Edith; Budeguer, Florencia; Ramos, Juan; Bardon, Alicia del Valle; Díaz, Sonia Beatriz; et al.; Structural factors of annonaceous acetogenins and their semisynthetic analogues related with the toxicity on Spodoptera frugiperda; Scientific Research an Academic Publisher; Journal of Agricultural Chemistry and Environment; 4; 2; 6-2015; 56-61
2325-7458
2325-744X
CONICET Digital
CONICET
Autor
Di Toto Blessing, Lilian Edith
Budeguer, Florencia
Ramos, Juan
Bardon, Alicia del Valle
Díaz, Sonia Beatriz
Brovetto, Margarita
Seoane, Gustavo
Neske, Adriana
Resumen
Toxic and nutritional effects of annonaceous acetogenins and their semisynthetic analogues on Spodoptera frugiperda were evaluated. Structural modification of the natural ACG, blocking the OH flanking THF with MOM, allowed us to suggest the mode of action of ACG in the membrane. Our study emphasizes the role of the flanking OH and acetyl groups of THF with the membrane hydrophilic polar head groups. They are essential structural factors in the ACG that facilitate the intermolecular interaction that dehydrates the membrane and makes it potentially toxic against Spodoptera frugiperda.