dc.creatorOliva, María De Los A.
dc.creatorSombra, Lorena Luján
dc.creatorOlsina, Roberto Antonio
dc.creatorMasi, Adriana Noemi
dc.date.accessioned2020-02-18T20:42:58Z
dc.date.accessioned2022-10-15T11:24:07Z
dc.date.available2020-02-18T20:42:58Z
dc.date.available2022-10-15T11:24:07Z
dc.date.created2020-02-18T20:42:58Z
dc.date.issued2005-09
dc.identifierOliva, María De Los A.; Sombra, Lorena Luján; Olsina, Roberto Antonio; Masi, Adriana Noemi; A new fluorescent assay for enalapril maleate; Springer/Plenum Publishers; Journal Of Fluorescence; 15; 5; 9-2005; 723-728
dc.identifier1053-0509
dc.identifierhttp://hdl.handle.net/11336/97983
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4380483
dc.description.abstractA new spectrofluorimetric method for the enalapril maleate monitoring was studied. Enalapril maleate was found to be highly photolabile. This drug was evaluated according to photodegradation assay at pH 2.5 and 6. Enalapril maleate was exposed to UVA-UVB radiations. Under these specific conditions was found as degradation product, the diketopiperazine. The modification of the fluorescent properties of enalapril maleate in solution after exposure UV-radiation and the degradation mechanisms were studied. The photodegradation was followed by the developed spectrofluorimetric assay.
dc.languageeng
dc.publisherSpringer/Plenum Publishers
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s10895-005-2979-3
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs10895-005-2979-3
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectDIKETOPIPERAZINE
dc.subjectENALAPRIL MALEATE
dc.subjectFLUORESCENCE
dc.subjectPHOTODEGRADATION
dc.titleA new fluorescent assay for enalapril maleate
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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