info:eu-repo/semantics/article
Citotoxicidad de Hidroxiapatita y su morfología en composites con Ti
Fecha
2013-01Registro en:
Comin, Romina; Reyna Musso, Laura A.; Cid, Mariana Paula; Oldani, Carlos Rodolfo; Salvatierra, Nancy Alicia; Citotoxicidad de Hidroxiapatita y su morfología en composites con Ti; Institute of Electrical and Electronics Engineers; IEEE Latin America Transactions; 11; 1-2013; 103-105
1548-0992
CONICET Digital
CONICET
Autor
Comin, Romina
Reyna Musso, Laura A.
Cid, Mariana Paula
Oldani, Carlos Rodolfo
Salvatierra, Nancy Alicia
Resumen
Hydroxyapatite (Ca10(PO4)6(OH)2 is the material used to improve osseointegration of implants in humans. Traditionally Ti-based implant is coated with hydroxyapatite, but this presents several problems such as, low fracture toughness of hydroxyapatite, generation of interfacial cracks during the deposition step and low adhesion ceramic /metal. Furthermore some studies reported that some excellent Ti-HA bio-composites could be fabricated by the powder metallurgy (PM) technology. In present study it was investigate the cytotoxicity of coralline and bovine hydroxyapatite. Topography of Ti-HA composites obtained by powder metallurgy was evaluated by scanning electron microscopy. The results showed that HA samples analyzed did not affect cell viability. Furthermore, a good integration of HA to the matrix of Ti was observed by microscopy studies