info:eu-repo/semantics/article
Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.
Fecha
2016-12Registro en:
Tomadoni, Bárbara María; Moreira, Maria del Rosario; Ponce, Alejandra Graciela; Anti-quorum sensing activity of natural compounds against Chromobacterium violaceum. 2016; 1(1): 43-48.; Ology Group; Annales Food Scince and Nutraceuticals; 1; 1; 12-2016; 43-48
2572-1194
CONICET Digital
CONICET
Autor
Tomadoni, Bárbara María
Moreira, Maria del Rosario
Ponce, Alejandra Graciela
Resumen
The resistance and potential pathogenesis of bacteria could be related to their ability to sense and respond topopulation density, termed quorum-sensing (QS). Inhibition of the QS system is considered as a novel strategyfor development of antipathogenic agents, especially for combating bacterial infections caused by antibioticresistantstrains. In this work, the anti-QS activity of vanillin, geraniol and pomegranate extract was tested againstChromobacterium violaceum. Moreover, the minimum QS inhibitory concentration (MQSIC) was estimated foreach agent. MQSIC?s found were very low (0.60 mg/mL for vanillin; 0.19 µL/mL for geraniol; and 25 µg/mL forpomegranate extract). Therefore, the natural agents tested in this work are good candidates for the developmentof anti-QS compounds with potential application for the control of bacterial diseases regulated by QS systems.