dc.contributor | Universidade Estadual Paulista (Unesp) | |
dc.contributor | Universidade Federal do Paraná (UFPR) | |
dc.date.accessioned | 2014-05-20T14:19:13Z | |
dc.date.accessioned | 2022-10-05T15:17:52Z | |
dc.date.available | 2014-05-20T14:19:13Z | |
dc.date.available | 2022-10-05T15:17:52Z | |
dc.date.created | 2014-05-20T14:19:13Z | |
dc.date.issued | 2010-02-01 | |
dc.identifier | Bioelectrochemistry. Lausanne: Elsevier B.V. Sa, v. 77, n. 2, p. 133-138, 2010. | |
dc.identifier | 1567-5394 | |
dc.identifier | http://hdl.handle.net/11449/25795 | |
dc.identifier | 10.1016/j.bioelechem.2009.07.010 | |
dc.identifier | WOS:000275232600010 | |
dc.identifier | 0000-0002-2296-1393 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3898850 | |
dc.description.abstract | A sensitive voltammetric method for trace measurements of isoniazid (INZ) in synthetic human urine sample is described. The method is based on its electroreduction at -0.98 V vs. Ag/AgCl on screen-printed carbon electrode (SPCE) modified with poly-L-histidine (PH). A film of good adherence on SPCE and electrocatalytic properties was obtained coating the electrode by histidine monomer electropolymerization process (SPCE/EPH). The electrochemical behavior of the modified SPCE was investigated by cyclic, linear sweep (LSV), differential pulse (DPV). square-wave voltammetry (SWV), and electrochemical impedance spectroscopy (EIS). Limits of detection of 5.0 x 10(-7) mol L(-1), 1.7 x 10(-7) mol L(-1) and 2.5 x 10(-7) mol L(-1) were estimated from LSV, DPV and SWV determinations, respectively. The method was successfully applied to the determination of INZ in human urine samples. (c) 2009 Elsevier B.V. All rights reserved. | |
dc.language | eng | |
dc.publisher | Elsevier B.V. Sa | |
dc.relation | Bioelectrochemistry | |
dc.relation | 3.789 | |
dc.relation | 0,850 | |
dc.rights | Acesso restrito | |
dc.source | Web of Science | |
dc.subject | Screen-printed electrode | |
dc.subject | Modified electrode | |
dc.subject | Poly-L-histidine | |
dc.subject | Isoniazid | |
dc.subject | Determination | |
dc.title | Determination of isoniazid in human urine using screen-printed carbon electrode modified with poly-L-histidine | |
dc.type | Artigo | |