Actas de congresos
Computational Biology tools in design of an agrochemical against Xylella fastidiosa.
FULAZ, S. F.
CABRINI, F. M.
Since its pathogenicity is related to bacterial motility, the protein PilT from the twitching motility system has been chosen as the host target. Using rational drug design, based on a detailed comprehension of the protein host structure, small molecules were designed in order to block the activity of the protein and provoke the loss of the bacterium pathogenicity.2015C.016.