article
Síndrome de sensibilidad a fármacos con eosinofilia y síntomas sistémicos debido a la carbamazepina. Caso pediátrico
Fecha
2018Autor
Pereira Ospina , Rocio del Pilar
Bejarano Quintero, Ana María
Suescun-Vargas, Jose-Miguel
Pinzon-Salamanca, Javier-Yesid
Institución
Resumen
Severe skin reactions include Stevens-Johnson Syndrome, toxic epidermal necrolysis and Drug reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome, which are uncommon in the pediatric population (incidence 1/1000-10 000 children), but they have bad prognosis. Drug-sensitive Syndrome with eosinophilia and systemic symptoms consists in rash, hematological abnormalities, lymphadenopathy and organ involvement. We report the case of a 12-year-old male patient who developed this pathology after initiating anticonvulsant therapy with carbamazepine. We consider that it is important to be aware of this disease and to include it among the differential diagnoses in patients with similar conditions because this syndrome is life-threatening. © 2018 Sociedad Argentina de Pediatria. All rights reserved.