Artículo de revista
Metabolic modelling and flux analysis of microorganisms from the Atacama Desert used in biotechnological processes
Fecha
2018Registro en:
Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology, Volumen 111, Issue 8, 2018, Pages 1479-1491
15729699
00036072
10.1007/s10482-018-1031-y
Autor
Razmilic, Valeria
Castro, Jean
Marchant, Francisca
Asenjo, Juan
Andrews, Barbara
Institución
Resumen
Metabolic modelling is a useful tool that enables the rational design of metabolic engineering experiments and the study of the unique capabilities of biotechnologically important microorganisms. The extreme abiotic conditions of the Atacama Desert have selected microbial diversity with exceptional characteristics that can be applied in the mining industry for bioleaching processes and for production of specialised metabolites with antimicrobial, antifungal, antiviral, antitumoral, among other activities. In this review we summarise the scientific data available of the use of metabolic modelling and flux analysis to improve the performance of Atacama Desert microorganisms in biotechnological applications.