Artículos de revistas
Role of adiponectin on antioxidant profile: evaluation during healthy and hypertensive disorders of pregnancy
Fecha
2016-07-03Registro en:
Blood Pressure, v. 25, n. 4, p. 241-243, 2016.
1651-1999
0803-7051
10.3109/08037051.2015.1134550
2-s2.0-84961212342
Autor
Universidade Estadual Paulista (Unesp)
Universidade Estadual de Campinas (UNICAMP)
Universidade de São Paulo (USP)
Institución
Resumen
The study of adipokines and oxidative stress has aided in understanding pre-eclampsia physiopathology. Therefore, our group aimed to evaluate the correlation between the adipokines (adiponectin and leptin) and the oxidative stress marker malondialdehyde–thiobarbituric acid reactive substances (MDA-TBARS) and antioxidant activity of plasma [ferric reducing ability of plasma (FRAP)] in healthy pregnant women and patients with gestational hypertension and pre-eclampsia. We found a significant negative correlation between MDA-TBARS and adiponectin (r = –0.40, p = 0.0042), suggesting a relationship between antioxidant levels and this adipokine in healthy pregnancies which is altered in patients with gestational hypertension or pre-eclampsia.