Otros
Crystal Structure of Bucain, a Three-Fingered Toxin from the Venom of the Malayan Krait (Bungarus candidus)
Fecha
2009-01-01Registro en:
Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 12, p. 1473-1477, 2009.
0929-8665
WOS:000271620200010
9162508978945887
0000-0003-2460-1145
Autor
Universidade Estadual Paulista (Unesp)
Natl Univ Singapore
Virginia Commonwealth Univ
Instituto Butantan
Institución
Resumen
Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 angstrom resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered neurotoxin possessing a positively charged AChR-binding site.