dc.creatorCovarrubias Gallardo, Cristián
dc.creatorDurán, Juan Pablo
dc.creatorMaureira, Miguel
dc.date.accessioned2018-07-17T16:41:08Z
dc.date.available2018-07-17T16:41:08Z
dc.date.created2018-07-17T16:41:08Z
dc.date.issued2018
dc.identifierMaterials Letters 219 (2018) 205–208
dc.identifierhttps://doi.org/10.1016/j.matlet.2018.02.075
dc.identifierhttps://repositorio.uchile.cl/handle/2250/149935
dc.description.abstractLithium carbonate nanoparticles were synthesized by facile chemical route in the presence of organic capping agents. Nanosized Li2CO3 particles of 86 nm in size were produced from LiOH solution and preferably using PVA as a capping agent. FTIR-ATR analysis revealed that Li2CO3 phase is formed during calcination of the freeze-dried synthesis product. In vitro tests shown that nanoparticle concentrations up to 600 mg/mL do not disturb cell viability and promote the osteogenic differentiation of stem cells by Li+ ions (9.7 mM) leached from the nanoparticle. The biological properties exhibited by the Li2CO3 nanoparticles make of them attractive for bone repair applications.
dc.languageen
dc.publisherElsevier
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
dc.sourceMaterials Letters
dc.subjectLithium nanoparticles
dc.subjectBioactive nanoparticles
dc.subjectBiomaterials
dc.subjectBone repair
dc.titleFacile synthesis of lithium carbonate nanoparticles with potential properties for bone repair applications
dc.typeArtículo de revista


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