Artículo de revista
Topical carbonic anhydrase inhibitors in macular edema associated with Alstrom syndrome
Fecha
2016Registro en:
Ophthalmic Genetics 37(4): 427-429
1381-6810
10.3109/13816810.2015.1094493
Autor
Larrañaga Fragoso, Paula
Pastora, Natalia
Bravo Ljubetic, Lucioano
Peralta, Jesús
Abelairas Gómez, José
Institución
Resumen
Background: Alstrom syndrome is a rare genetic ciliopathy caused by a mutation in the ALMS1 gene. The syndrome is characterized by cone-rod dystrophy, dilated myocardiopathy, childhood obesity and sensorineural hearing loss. To date, cystoid macular edema has not been reported.
Methods: A female affected by Alstrom syndrome developed bilateral cystoid macular edema evidenced by optical coherence tomography. A topical carbonic anhydrase inhibitor was prescribed.
Results: Complete resolution of the cystoid macular edema was achieved, though visual acuity did not improve.
Conclusions: Topical carbonic anhydrase inhibitors may have a role in the treatment of macular edema in syndromic retinal dystrophies such as Alstrom syndrome