Artículo de revista
Candidiasis invasoras en el paciente crítico adulto
Fecha
2011-02Registro en:
REVISTA CHILENA DE INFECTOLOGIA Volume: 28 Issue: 1 Pages: 41-49 Published: FEB 2011
0716-1018
Autor
Tobar Almonacid, Eduardo
Olivares Castillo, Roberto
Silva Ojeda, Francisco
Luppi Norambuena, Mario
Gaete G., Pablo
Institución
Resumen
Invasive infections by Candida strains are a relevant pathology in critically ill patients. Candida should be considered where a high risk of infection is present for a critical early diagnosis. Despite the incorporation of new drugs in the therapeutic armamentarium over the last decade, mortality remains high. The key in improving clinical outcomes of these patients are the use of early effective therapies that offer coverage against different strains of Candida: C. albicans and non-albicans. Recent international guidelines suggest empiric therapy with echinocandins in suspected invasive candidiasis in this patient population. This group of drugs adequately documented clinical efficacy and safe use in these patients. The emergence of new echinocandins could improve access to these drugs by reducing their cost.