Artículo de revista
ESR, electrochemical and reactivity studies of antitrypanosomal palladium thiosemicarbazone complexes
Fecha
2008-08Registro en:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Volume 70, Issue 3,, Pages 519-523, 2008
1386-1425
Autor
Otero, Lucía
Folch, Christian
Barriga, Germán
Rigol Olsen, Carolina
Opazo, Lucía
Vieites, Marisol
Gambino, Dinorah
Cerecetto, Hugo
Norambuena, Ester
Olea Azar, Claudio
Institución
Resumen
Cyclic voltammetry (CV) and electron spin resonance (ESR) techniques were used in the investigation of novel palladium complexes with
bioactive thiosemicarbazones derived from 5-nitrofurane or 5-nitrofurylacroleine. Sixteen palladium complexes grouped in two series of the
formula [PdCl2HL] or [PdL2] were studied. ESR spectra of the free radicals obtained by electrolytic reduction were characterized and analyzed.
The ESR spectra showed two different hyperfine patterns. The stoichiometry of the complexes does not seem to affect significantly the hyperfine
constants however we observed great differences between 5-nitrofurane and 5-nitrofurylacroleine derivatives. The scavenger properties of this
family of compounds were lower than Trolox.