Artículos de revistas
Monoaminergic, Ion Channel and Enzyme Inhibitory Activities of Natural Aporphines, their Analogues and Derivatives
Fecha
2007-12-01Registro en:
Natural Product Communications Vol. 3 (4) 2008.
1555-9475
Autor
Cassels Niven, Bruce
Asencio, Marcelo
Institución
Resumen
The aporphine alkaloids constitute the second-largest group of isoquinoline alkaloids. Nevertheless, only a relatively small
number of natural aporphines and their derivatives have been studied from a pharmacological viewpoint. Here we review the
pharmacological data available for these compounds as related to their dopaminergic, noradrenergic and serotonergic activities,
and also some results pertaining to their effects on ion channels and enzymes.