Artículo de revista
Genetic network during neural crest induction: From cell specification to cell survival
Fecha
2005-12Registro en:
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
1084-9521
Autor
Steventon, Ben
Carmona Fontaine, Carlos
Mayor Caro, Roberto
Institución
Resumen
The concerted action of extracellular signals such as BMP, Wnt, FGF, RA and Notch activate a genetic program required to transform a naive ectodermal cell into a neural crest cell. In this review we will analyze the extracellular signals and the network of transcription factors that are required for this transformation. We will propose the division of this complex network of factors in two main steps: an initial cell specification step followed by a maintenance or cell survival step.