masterThesis
Caracterización clínica, citoquímica y microbiológica de pacientes cirróticos con peritonitis bacteriana en la Fundación Cardioinfantil
Fecha
2014Autor
Salinas Gómez, Diana Carolina
Institución
Resumen
Introduction: Spontaneous bacterial peritonitis is the most common infection in cirrhotic patients usually caused by Escherichia coli. Some risk factors related to the occurrence and recurrence of peritoneal infection have been described, so early implementation of preventive strategies could impact on reducing morbidity and mortality. Methodology : Descriptive, case series, we search the results of cytochemical study of ascitic fluid of cirrhotic patients between 2009 and 2013, by selecting those compatible with infection, in order to collect the clinical and laboratory information to conform the database and analyze them. Results : Alcohol is the leading cause of cirrhosis in infected patients, the main organism isolated was Escherichia coli, documenting 78% of negative cultures, 20 % higher than that reported in the literature. Ampicillin sulbactam was the antibiotic of choice in 65 % of cases , 61% of these continued without requiring change of it. Discussion : This study confirms alcohol as the main etiology of cirrhosis in our country and the Escherichia coli multisusceptible as main agent. Due to the low percentage of required changes of ampicillin sulbactam during adjustment of therapy it may suggest this antibiotic in the management, however it requires further studies to compare their effectiveness in relation to third-generation cephalosporins. Similarly We should prioritize the use of blood culture bottles crops to increase the amount of insolation and optimize antibiotic therapy according to the obtained microorganism.