Índices neutrófilos/linfocitos y plaquetas/linfocitos como predictores de preeclampsia en la Clínica Universitaria Colombia
Campo Elíaz, Jorge Luís
Rangel Ramos, Víctor Saúl
Introduction: Preeclampsia affects 5 to 8% of pregnancies and is considered the second cause of maternal death worldwide, reaching 10-15% of cases. Recently, some authors propose the use of neutrophil/lymphocyte (NLR) and platelet/lymphocyte (PLR) ratios as prognostic markers of preeclampsia. Determining the usefulness of these indices in our country could help the timely identification of patients at risk, especially in places with limited resources and difficult access to health services. Materials and methods: A prediction study was carried out where the patients who consulted the University Clinic Colombia in the period between 2015-2017 were selected, forming two groups of analysis. The neutrophil/lymphocyte and platelet/lymphocyte ratios were calculated from the haemograms performed in the first trimester of pregnancy and their association with the occurrence of preeclampsia with or without criteria of severity was analyzed, calculating the operational characteristics of the test. Results: When comparing the neutrophil/lymphocyte and platelet/lymphocyte ratios to determine relationship with preeclampsia, between the two groups no significant differences were found between the NLR medians (p = 0.368, Mann Whitney test), nor in PLR (p = 0.608, Mann Whitney Test). The predictive capacity of severe preeclampsia that was found with the NLR, showed a non-significant predictive area of 50.9% for preeclampsia (p = 0.819, 95% CI: 43.4-58.4%) and the PLR a non-significant predictive area of 54.6% for severe preeclampsia (p = 0.235, 95% CI: 47.2 - 62.0%).