dc.creator | Gomez, Federico Hernan | |
dc.creator | Loeschcke, Volker | |
dc.creator | Norry, Fabian Marcelo | |
dc.date.accessioned | 2017-07-05T21:45:33Z | |
dc.date.accessioned | 2018-11-06T13:51:02Z | |
dc.date.available | 2017-07-05T21:45:33Z | |
dc.date.available | 2018-11-06T13:51:02Z | |
dc.date.created | 2017-07-05T21:45:33Z | |
dc.date.issued | 2012-08 | |
dc.identifier | Gomez, Federico Hernan; Loeschcke, Volker; Norry, Fabian Marcelo; QTL for survival to UV-C radiation in Drosophila melanogaster; Taylor & Francis; International Journal Of Radiation Biology; 89; 7; 8-2012; 583-589 | |
dc.identifier | 0955-3002 | |
dc.identifier | http://hdl.handle.net/11336/19708 | |
dc.identifier | CONICET Digital | |
dc.identifier | CONICET | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1880102 | |
dc.description.abstract | Purpose: The aim of this study was to investigate tolerance to UV-C (ultraviolet C, 280–100 nm) radiation in Drosophila melanogaster, implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. Materials and methods: We performed a QTL scan in D. melanogaster recombinant inbred lines (RIL) constructed from parental stocks derived from a crossing between northern and southern hemisphere populations that segregated substantial genetic variation in thermal resistance in a previous study. Here, two experimental treatments were implemented: Continuous and cyclic UV-C radiation. Results: Significant QTL were detected on all three major chromosomes. Among these, multiple trait composite interval mapping revealed a significant QTL in the pericentromeric region of chromosome 2, a genome region consistently implicated in thermotolerance in previous studies. Conclusions: This study shows substantial genetic variation for UV-C radiation resistance in D. melanogaster, with QTL for survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. | |
dc.language | eng | |
dc.publisher | Taylor & Francis | |
dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3109/09553002.2012.711503 | |
dc.relation | info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/full/10.3109/09553002.2012.711503 | |
dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.subject | Ultraviolet radiation | |
dc.subject | Multiple trait mapping | |
dc.subject | Environmental stress | |
dc.subject | Thermotolerance | |
dc.title | QTL for survival to UV-C radiation in Drosophila melanogaster | |
dc.type | Artículos de revistas | |
dc.type | Artículos de revistas | |
dc.type | Artículos de revistas | |