info:eu-repo/semantics/article
The role of N-β-alanyldopamine synthase in the innate immune response of two insects
Fecha
2007-11Registro en:
Schachter, Julieta; Pérez, Martín Mariano; Quesada Allue, Luis Alberto; The role of N-β-alanyldopamine synthase in the innate immune response of two insects; Pergamon-Elsevier Science Ltd; Journal of Insect Physiology; 53; 11; 11-2007; 1188-1197
0022-1910
1879-1611
CONICET Digital
CONICET
Autor
Schachter, Julieta
Pérez, Martín Mariano
Quesada Allue, Luis Alberto
Resumen
Insects trigger a multifaceted innate immune response to fight microbial infections. We show that in the yellow mealworm, Tenebrio molitor, septic injuries induce the synthesis of N-b-alanyldopamine (NBAD), which is known as the main sclerotization precursor of insect brown cuticles. We demonstrate that NBAD synthase is induced in the epidermis of the mealworm and of the Medfly, Ceratitis capitata, by infection with Escherichia coli. Our results indicate that synthesis of NBAD seems to be a novel component of the overall innate immune response in insects.