info:eu-repo/semantics/article
Zuccagnia punctata: A Review of its Traditional Uses, Phytochemistry, Pharmacology and Toxicology
Fecha
2016-01Registro en:
Isla, Maria Ines; Moreno, María Alejandra; Nuño, Gabriela; Rodriguez, Ivana Fabiola; Carabajal, Monica Patricia Antonella; et al.; Zuccagnia punctata: A Review of its Traditional Uses, Phytochemistry, Pharmacology and Toxicology; Natural Products; Natural Product Communications; 11; 1-2; 1-2016; 1749-1755
1934-578X
CONICET Digital
CONICET
Autor
Isla, Maria Ines
Moreno, María Alejandra
Nuño, Gabriela
Rodriguez, Ivana Fabiola
Carabajal, Monica Patricia Antonella
Alberto, Maria Rosa
Zampini, Iris Catiana
Resumen
Zuccagnia punctata Cav. (Fabaceae, Caesalpiniaceae) is a plant with a long history of use in Argentine traditional medicines; it belongs to a monotypic genus, and is an endemic species of Argentina. This review provides a comprehensive overview of the traditional uses, phytochemistry, pharmacological activity and toxicology of Z. punctata. A wide range of traditional uses are cited in the literature such as antibacterial, antifungal, anti-inflammatory, and antitumor, among others. Pharmacological studies to date have demonstrated significant activities that support the traditional uses of this plant. No human clinical trials had been completed up to the time of this review and no toxic effect had been detected in animals. Compounds from different chemical groups have been isolated such as phenolic compounds and essential oils. Plant extracts and phytochemicals isolated exhibit a broad range of activities, anti-inflammatory, antibacterial, antifungal, antigenotoxic, antioxidant, antiulcer, and nematicidal. The main bioactive phytochemicals in the aerial parts (leaf, stem and flower) were identified as 2´, 4´-dihydroxy-3´-methoxychalcone and 2´, 4´-dihydroxychalcone and were proposed as chemical markers. Consequently, standardized dry extracts of aerial parts of Z. puntacta could be used in herbal medicinal products. Also, they could be included in phytotherapeutic preparations such as capsules, creams, and gels, and for microencapsulation.