dc.creatorDuran, N
dc.creatorMarcucci, M C
dc.creatorGatti, M S
dc.creatorLeite, L C
dc.date1990-Mar
dc.date2015-11-27T12:18:13Z
dc.date2015-11-27T12:18:13Z
dc.date.accessioned2018-03-29T00:50:48Z
dc.date.available2018-03-29T00:50:48Z
dc.identifierJournal Of Photochemistry And Photobiology. B, Biology. v. 4, n. 4, p. 371-8, 1990-Mar.
dc.identifier1011-1344
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/2111383
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/193663
dc.identifier2111383
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1293896
dc.descriptionStrains of Escherichia coli which lack 4-thiouridine (S4U) exhibit a higher survival rate than their wild-type parents which contain S4U after treatment with enzyme-generated triplet indole-3-aldehyde. In a similar manner to results obtained with monochromatic 334 nm UV light, the survival is related to single-strand breakage of DNA in E. coli containing the pBR 322 plasmid. The effects of the excited states generated by an enzymatic system suggest that S4U is an important chromophore in the lethal effects observed. The results also suggest that the energy transferred from triplet indole-3-aldehyde to S4U may also be passed from S4U of t-RNA to DNA, possibly through a singlet oxygen intermediate generated by excited S4U, resulting in a decrease in the survival rate of E. coli containing S4U. These results emphasize the importance of excited states in biological systems.
dc.description4
dc.description371-8
dc.languageeng
dc.relationJournal Of Photochemistry And Photobiology. B, Biology
dc.relationJ. Photochem. Photobiol. B, Biol.
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectDna Damage
dc.subjectDna, Bacterial
dc.subjectEnergy Metabolism
dc.subjectEscherichia Coli
dc.subjectIndoles
dc.subjectMutation
dc.subjectOxygen
dc.subjectPhotochemistry
dc.subjectThiouridine
dc.titleDifferent Lethal Effects By Enzyme-generated Triplet Indole-3-aldehyde In Different Escherichia Coli Strains.
dc.typeArtículos de revistas


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