Depression in patients with Parkinson's disease: Impact on functioning

dc.creatorStella, F
dc.creatorBanzato, CEM
dc.creatorQuagliato, EMAB
dc.creatorViana, MA
dc.date2008
dc.dateSEP 15
dc.date2014-11-17T12:00:23Z
dc.date2015-11-26T17:37:25Z
dc.date2014-11-17T12:00:23Z
dc.date2015-11-26T17:37:25Z
dc.date.accessioned2018-03-29T00:19:06Z
dc.date.available2018-03-29T00:19:06Z
dc.identifierJournal Of The Neurological Sciences. Elsevier Science Bv, v. 272, n. 41671, n. 158, n. 163, 2008.
dc.identifier0022-510X
dc.identifierWOS:000259131200023
dc.identifier10.1016/j.jns.2008.05.018
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/79506
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/79506
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/79506
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1285956
dc.descriptionDepression is a frequently observed neuropsychiatric phenomenon in Parkinson's disease (PD) and it has been lately considered as a manifestation of such disease. The aim of the study was to investigate the relationship between depression and clinical aspects of PD and to assess the impact of the co-occurrence of such condition on the burden imposed by PD. Fifty Outpatients diagnosed with idiopathic PD according to the London Brain Bank criteria were examined. PD was evaluated using Hoehn & Yahr staging (H&Y), United Parkinson's Disease Rating Scale (UPDRS) and Schwab & England (S&E) functional capacity evaluation. A semi-structured clinical interview was used. The diagnosis of PD was made by neurologist experts on movement disorders, and the diagnosis of depression was trade by a psychiatrist, according to the ICD-10 diagnostic criteria. Depressive symptoms were additionally measured using the Montgomery-Asberg Depression Scale. The analysis of quantitative data was performed using descriptive statistics, Univariate linear regression, T-Student Test and ANOVA. Seventeen (34%) patients were diagnosed as clinically depressed and, when compared to the non-depressed ones, presented the following results: H&Y: 3.2 vs. 2.8; UPDRS total: 75.7 vs. 65.3; S&E: 53.5% vs. 65.8% and PD duration: 114.4 months vs. 125.8 months. Depressed patients showed more advanced staging (H&Y), a more severe global clinical condition (UPDRS) and also a greater decrease in their functional capacity (S&E). These data reinforce the hypothesis that depression is associated to poorer functioning in patients with PD. (C) 2008 Elsevier B.V All rights reserved.
dc.description272
dc.description41671
dc.description158
dc.description163
dc.languageen
dc.publisherElsevier Science Bv
dc.publisherAmsterdam
dc.publisherHolanda
dc.relationJournal Of The Neurological Sciences
dc.relationJ. Neurol. Sci.
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectParkinson's disease
dc.subjectdepression
dc.subjectclinical condition
dc.subjectQuality-of-life
dc.subjectMajor Depression
dc.subjectRisk-factors
dc.subjectScale
dc.subjectOnset
dc.subjectOutpatients
dc.subjectPopulation
dc.subjectPsychosis
dc.subjectAccuracy
dc.subjectDementia
dc.titleDepression in patients with Parkinson's disease: Impact on functioning
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución