Monthly variation of multiple sclerosis activity in the southern hemisphere: analysis from 996 relapses in Brazil

dc.creatorDamasceno, A
dc.creatorVon Glehn, F
dc.creatorde Deus-Silva, L
dc.creatorDamasceno, BP
dc.date2012
dc.dateAPR
dc.date2014-08-01T18:42:39Z
dc.date2015-11-26T17:30:46Z
dc.date2014-08-01T18:42:39Z
dc.date2015-11-26T17:30:46Z
dc.date.accessioned2018-03-29T00:17:37Z
dc.date.available2018-03-29T00:17:37Z
dc.identifierEuropean Journal Of Neurology. Wiley-blackwell, v. 19, n. 4, n. 660, n. 662, 2012.
dc.identifier1351-5101
dc.identifierWOS:000301493100024
dc.identifier10.1111/j.1468-1331.2011.03543.x
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/82367
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/82367
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1285582
dc.descriptionBackground and purpose: Seasonal variations of multiple sclerosis (MS) activity have been reported, however, most data come from studies in the northern hemisphere. Methods: We reviewed medical records of MS patients living in Campinas region, Brazil. The first symptoms' date was defined as the relapse month. Climatic information included UV radiation index, median temperature, rainfall, and humidity. Results: Two hundred and nine patients were included. The incidence of relapses was highest in January (11.2%) and December (10.4%) and lowest in November (5.7%) and October (7.0%) (P < 0.015). The months with highest incidence of relapses (December-January) had higher UV radiation index and humidity rates (P = 0.032 and 0.040, respectively). Conclusion: Most exacerbations were in the spring/summer transition, which also showed higher UV radiation index and humidity rate. Along with other environmental factors, seasonal fluctuation contributes to MS activity.
dc.description19
dc.description4
dc.description660
dc.description662
dc.languageen
dc.publisherWiley-blackwell
dc.publisherMalden
dc.publisherEUA
dc.relationEuropean Journal Of Neurology
dc.relationEur. J. Neurol.
dc.rightsfechado
dc.rightshttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.sourceWeb of Science
dc.subjectenvironmental factors
dc.subjectmultiple sclerosis
dc.subjectrelapses
dc.subjectseasonal variations
dc.subjectUV radiation
dc.subjectSeasonal-variation
dc.subjectDisease-activity
dc.subjectExacerbations
dc.titleMonthly variation of multiple sclerosis activity in the southern hemisphere: analysis from 996 relapses in Brazil
dc.typeArtículos de revistas


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