dc.creator | Lollo P.C.B. | |
dc.creator | Cruz A.G. | |
dc.creator | Morato P.N. | |
dc.creator | Moura C.S. | |
dc.creator | Carvalho-Silva L.B. | |
dc.creator | Oliveira C.A.F. | |
dc.creator | Faria J.A.F. | |
dc.creator | Amaya-Farfan J. | |
dc.date | 2012 | |
dc.date | 2015-06-25T20:23:20Z | |
dc.date | 2015-11-26T15:18:50Z | |
dc.date | 2015-06-25T20:23:20Z | |
dc.date | 2015-11-26T15:18:50Z | |
dc.date.accessioned | 2018-03-28T22:28:26Z | |
dc.date.available | 2018-03-28T22:28:26Z | |
dc.identifier | | |
dc.identifier | Journal Of Dairy Science. , v. 95, n. 7, p. 3549 - 3558, 2012. | |
dc.identifier | 220302 | |
dc.identifier | 10.3168/jds.2011-5124 | |
dc.identifier | http://www.scopus.com/inward/record.url?eid=2-s2.0-84862509337&partnerID=40&md5=57927785472a3ca195b34baa23d098c1 | |
dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/90015 | |
dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/90015 | |
dc.identifier | 2-s2.0-84862509337 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1259626 | |
dc.description | Intense physical activity results in a substantial volume of stress and hence a significant probability of immunosuppression in athletes, with milk proteins being, perhaps, the most recommended protein supplements. Consumption of a probiotic cheese can attenuate immune suppression induced by exhausting exercise in rats. A popular Brazilian fresh cheese (Minas Frescal cheese) containing Lactobacillus acidophilus LA14 and Bifidobacterium longum BL05 was fed for 2 wk to adult Wistar rats, which then were brought to exhaustion on the treadmill. Two hours after exhaustion, the rats were killed and material was collected for the determination of serum uric acid, total and high-density lipoprotein cholesterol fraction, total protein, triacylglycerols, aspartate aminotransferase, alanine aminotransferase, creatine kinase, and blood cell (monocyte, lymphocyte, neutrophil, and leukocyte) counts. Exercise was efficient in reducing lymphocyte counts, irrespective of the type of ingested cheese, but the decrease in the group fed the probiotic cheese was 22% compared with 48% in the animals fed regular cheese. Monocyte counts were unaltered in the rats fed probiotic cheese compared with a significant decrease in the rats fed the regular cheese. Most importantly, ingestion of the probiotic cheese resulted in a >100% increase in serum high-density lipoprotein cholesterol and a 50% decrease in triacylglycerols. We conclude that probiotic Minas Frescal cheese may be a viable alternative to enhance the immune system and could be used to prevent infections, particularly those related to the physical overexertion of athletes.. © 2012 American Dairy Science Association. | |
dc.description | 95 | |
dc.description | 7 | |
dc.description | 3549 | |
dc.description | 3558 | |
dc.description | Abcouwer, S.F., Effects of glutamine on immune cells (2000) Nutrition, 16, pp. 67-69 | |
dc.description | (2009), http://www.abril.com.br/noticias/ciencia-saude/cresce-numero-brasileiros-praticam-atividade-fisica-433158.shtml, Agencia Estado. Cresce número de brasileiros que praticam atividade física. Accessed Jan. 30, 2012Albenzio, M., Santillo, A., Caroprese, M., Marino, R., Trani, A., Faccia, M., Biochemical patterns in ovine cheese: Influence of probiotic strains (2010) J. Dairy Sci., 93, pp. 3487-3496 | |
dc.description | (2002) Official Methods of Analysis, , AOAC, Association of Official Analytical Chemists International, Gaithersburg, MD | |
dc.description | Asemi, Z., Samimi, M., Tabasi, Z., Talebian, P., Azarbad, Z., Hydarzadeh, Z., Esmaillzadeh, A., Effect of daily consumption of probiotic yoghurt on lipid profiles in pregnant women: A randomized controlled clinical trial (2011) J. Matern. Fetal Neonat., , 10.3109/14767058.2011.640372 | |
dc.description | Ataie-Jafari, A., Larijani, B., AlaviMajd, H., Tahbaz, F., Cholesterol-lowering effect of probiotic yogurt in comparison with ordinary yogurt in mildly to moderately hypercholesterolemic subjects (2009) Ann. Nutr. Metab., 54, pp. 22-27 | |
dc.description | Berg, A., Muller, H.M., Rathmann, S., Deibert, P., The gastrointestinal system an essential target organ of the athlete's health and physical performance (1999) Exerc. Immunol. Rev., 5, pp. 78-95 | |
dc.description | Bergamini, C.V., Hynes, E.R., Quiberoni, A., Suárez, V.B., Zalazar, C.A., Probiotic bacteria as adjunct starters: Infl{ligature}uence of the addition methodology on their survival in a semi-hard Argentinean cheese (2005) Food Res. Int., 38, pp. 597-604 | |
dc.description | Blannin, A.K., Chatwin, L.J., Cave, R., Gleeson, M., Effects of submaximal cycling and long-term endurance training on neutrophil phagocytic activity in middle-aged men (1996) Br. J. Sports Med., 30, pp. 125-129 | |
dc.description | Bloomer, R.J., Effect of exercise on oxidative stress biomarkers (2008) Adv. Clin. Chem., 46, pp. 1-50 | |
dc.description | Borchers, A.T., Selmi, C., Meyers, F.J., Keen, C.L., Gershwin, M.E., Probiotics and immunity (2009) J. Gastroenterol., 44, pp. 26-46 | |
dc.description | Brenner, I., Shek, P.N., Zamecnik, J., Shephard, R.J., Stress hormones and the immunological responses to heat and exercise (1998) Int. J. Sports Med., 19, pp. 130-143 | |
dc.description | Buriti, F.C.A., Rocha, J.S., Assis, E.G., Saad, S.M.I., Probiotic potential of Minas fresh cheese prepared with the addition of Lactobacillus paracasei (2005) Lebenson. Wiss. Technol., 38, pp. 173-180 | |
dc.description | Buriti, F.C.A., Rocha, J.S., Saad, S.M.I., Incorporation of Lactobacillus acidophilus in Minas fresh cheese and its implications for textural and sensorial properties during storage (2005) Int. Dairy J., 15, pp. 1279-1288 | |
dc.description | Cruz, A.G., Buriti, F.C.A., Souza, C.B.H., Faria, J.A.F., Saad, S.M.I., Probiotic cheese: Health benefi{ligature}ts, technological and stability aspects (2009) Trends Food Sci. Technol., 20, pp. 344-354 | |
dc.description | Cruz, A.G., Cadena, R.S., Faria, J.A.F., Bolini, H.M.A., Dantas, C., Ferreira, M.M.C., Deliza, R., PARAFAC: Adjustment for modeling consumer study covering probiotic and conventional yogurt (2012) Food Res. Int., 45, pp. 211-215 | |
dc.description | Cruz, A.G., Cadena, R.S., Faria, J.A.F., Oliveira, C.A.F., Cavalcanti, R.N., Bona, E., Bolini, H.M.A., Da Silva, M.A.A.P., Consumer acceptability and purchase intent of probiotic yoghurt with added glucose oxidase using sensometrics, artificial neural networks and logistic regression (2011) Int. J. Dairy Technol., 64, pp. 549-556 | |
dc.description | Cruz, A.G., Castro, W.F., Faria, J.A.F., Bogusz, S., Granato, S.D., Celeguini, R.M.S., Lima-Pallone, J., Godoy, H.T., Glucose oxidase: A potential option to decrease the oxidative stress in stirred probiotic yogurt (2012) Lebenson. Wiss. Technol., 47, pp. 512-515 | |
dc.description | Cruz, A.G., Castro, W.F., Faria, J.A.F., Lollo, P.C.B., Amaya-Farfán, J., Freitas, M.Q., Rodrigues, D., Godoy, H.T., Probiotic yogurts manufactured with increased glucose oxidase levels: Postacidification, proteolytic patterns, survival of probiotic microorganisms, production of organic acid and aroma compounds (2012) J. Dairy Sci., 95, pp. 2261-2269 | |
dc.description | Cruz, A.G., Faria, J.A.F., Walter, E.H.M., Andrade, R.R., Cavalcanti, R.N., Oliveira, C.A.F., Granato, D., Processing optimization of probiotic yogurt containing glucose oxidase using response surface methodology (2010) J. Dairy Sci., 93, pp. 5059-5068 | |
dc.description | De Almeida, M.H.B., Zoellner, S.S., Cruz, A.G., Moura, M.R.L., De Carvalho, L.M.J., Freitas, M.C.J., Sant'Ana, A.D.S., Potentially probiotic açaí yogurt (2008) Int. J. Dairy Technol., 61, pp. 178-182 | |
dc.description | de Vrese, M., Winkler, P., Rautenberg, P., Harder, T., Noah, C., Laue, C., Ott, S., Schrezenmeir, J., Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial (2006) Vaccine, 24, pp. 6670-6674 | |
dc.description | de Vrese, M., Schrezenmeir, J., Probiotics, prebiotics, and synbiotics (2008) Adv. Biochem. Eng. Biotechnol., 111, pp. 1-66 | |
dc.description | Ejtahed, H.S., Mothtadi-Nia, J., Homayouni-Rad, A., Niafar, M., Asghari-Jafarabadi, M., Mofid, V., Akbarian-Moghari, A., Effect of probiotic yogurt containing Lactobacillus acidophilus and Bifidobacterium lactis on lipid profile in individuals with type 2 diabetes mellitus (2011) J. Dairy Sci., 94, pp. 3288-3294 | |
dc.description | Espírito Santo, A.P.D., Silva, R.C., Soares, F.A.S.M., Anjos, D., Gioielli, L.A., Oliveira, M.N., Açai pulp addition improves fatty acid profile and probiotic viability in yoghurt (2010) Int. Dairy J., 20, pp. 415-422 | |
dc.description | Fabian, E., Elmadfa, I., Influence of daily consumption of probiotic and conventional yoghurt on the plasma lipid profile in young healthy women (2006) Ann. Nutr. Metab., 50, pp. 387-393 | |
dc.description | Fritzen-Freire, C.B., Muller, C.M.O., Laurindo, J.B., Amboni, R.M.C., Prudêncio, E.S., The effect of direct acidifi{ligature}cation on the microbiological physicochemical and sensory properties of probiotic Minas Frescal cheese (2010) Int. J. Dairy Technol., 63, pp. 561-568 | |
dc.description | Fritzen-Freire, C.B., Muller, C.M.O., Laurindo, J.B., Prudêncio, E.S., The influence of Bifidobacterium Bb-12 and lactic acid incorporation on the properties of Minas Frescal cheese (2010) J. Food Eng., 96, pp. 621-627 | |
dc.description | Gill, H.S., Cross, M.L., Probiotics and immune function (2002) Nutrition and Immune Function, pp. 251-272. , CABI, Oxford, UK, P.C. Calder, C.J. Field, H.S. Gill (Eds.) | |
dc.description | Gill, R., Tsung, A., Billiar, T., Linking oxidative stress to inflammation: Toll-like receptors (2010) Free Radic. Biol. Med., 48, pp. 1121-1132 | |
dc.description | Gleeson, M., Mucosal immunity and respiratory illness in elite athletes (2000) Int. J. Sports Med., 21 (SUPPL. 1), pp. S33-S43 | |
dc.description | Gleeson, M., Immune function in sport and exercise (2007) J. Appl. Physiol., 103, pp. 693-699 | |
dc.description | Gomes, A.A., Braga, S.P., Cruz, A.G., Cadena, R.S., Faria, J.A.F., Lollo, P.C., Amaya-Farfan, J., Bolini, H.M.A., Effect of the inoculation level of L. acidophilus in probiotic cheese on the physicochemical features and sensory performance towards commercial cheeses (2011) J. Dairy Sci., 94, pp. 4777-4786 | |
dc.description | Gomes, A.P., Cruz, A.G., Cadena, R.S., Granato, R.M.S., Celeghini, D., Faria, J.A.F., Bolini, H.M.A., Pollonio, M.A.R., Low sodium Minas fresh cheese manufacture: Effect of the partial replacement of NaCl with KCl (2011) J. Dairy Sci., 94, pp. 2701-2706 | |
dc.description | Granato, D., Branco, G.F., Cruz, A.G., Faria, J.A.F., Shah, N.P., Probiotic dairy products as functional foods (2010) Comp. Rev. Food Sci. Food Saf., 9, pp. 455-470 | |
dc.description | Guarino, A., Lo Vecchio, A., Canani, R.B., Probiotics as prevention and treatment for diarrhea (2009) Curr. Opin. Gastroenterol., 25, pp. 18-23 | |
dc.description | Hamer, M., Wolvers, D., Albers, R., Using stress models to evaluate immuno-modulating effects of nutritional intervention in healthy individuals (2004) J. Am. Coll. Nutr., 23, pp. 637-646 | |
dc.description | Hatakka, K., Ahola, A.J., Yli-Knuuttila, H., Richardson, M., Poussa, T., Meurman, J.H., Korpela, R., Probiotics reduce the prevalence of oral Candida in the elderly a randomized controlled trial (2007) J. Dent. Res., 86, pp. 125-130 | |
dc.description | Hoffman-Goetz, L., Pedersen, B.K., Exercise and the immune system: A model of the stress response? (1994) Immunol. Today, 15, pp. 382-387 | |
dc.description | Huang, Y., Zheng, Y., The probiotic Lactobacillus acidophilus reduces cholesterol absorption through the down-regulation of Niemann-Pick C1-like 1 in Caco-2 cells (2010) Br. J. Nutr., 103, pp. 473-478 | |
dc.description | Ibrahim, F., Ruvio, S., Granlund, L., Salminen, S., Viitanen, M., Ouwehand, A.C., Probiotics and immunosenescence: Cheese as a carrier (2010) FEMS Immunol. Med. Microbiol., 59, pp. 53-59 | |
dc.description | Im, S.S., Yousef, L., Blaschitz, C., Liu, J.Z., Edwards, R.A., Young, S.G., Raffatellu, M., Osborne, T.F., Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a (2011) Cell Metab., 13, pp. 540-549 | |
dc.description | Inouye, M., Silander, K., Hamalainen, E., Salomaa, V., Harald, K., Jousilahti, P., Mannisto, S., Peltonen, L., An immune response network associated with blood lipid levels (2010) PLoS Genet., 6. , e1001113 | |
dc.description | Karimi, R., Mortazavian, A.M., Cruz, A.G., Viability of probiotic microorganisms in cheese during production and storage: A review (2011) J. Dairy Sci. Technol., 91, pp. 283-308 | |
dc.description | Keil, D., Luebke, R.W., Pruett, S.B., Quantifying the relationship between multiple immunological parameters and host resistance: Probing the limits of reductionism (2001) J. Immunol., 167, pp. 4543-4552 | |
dc.description | Knight, J.A., Review: Free radicals, antioxidants, and the immune system (2000) Ann. Clin. Lab. Sci., 30, pp. 145-158 | |
dc.description | Lahtinen, S.J., Forssten, S., Aakko, J., Granlund, L., Rautonen, N., Salminen, S., Viitanen, M., Ouwehand, A.C., Probiotic cheese containing Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus NCFM (®) modifies subpopulations of fecal lactobacilli and Clostridium difficile in the elderly (2012) Age (Dordr.), 34, pp. 133-143 | |
dc.description | Larkin, T.A., Astheimer, L.B., Price, W.E., Dietary combination of soy with a probiotic or prebiotic food significantly reduces total and LDL cholesterol in mildly hypercholesterolaemic subjects (2009) Eur. J. Clin. Nutr., 63, pp. 238-245 | |
dc.description | Lima-Silva, A.E., De-Oliveira, F.R., Nakamura, F.Y., Gevaerd, M.S., Effect of carbohydrate availability on time to exhaustion in exercise performed at two different intensities (2009) Braz. J. Med. Biol. Res., 42, pp. 404-412 | |
dc.description | Mackinnon, L.T., Chronic exercise training effects on immune function (2000) Med. Sci. Sports Exerc., 32, pp. S369-S376 | |
dc.description | Madureira, A.R., Brandão, T., Pintado, A.M., Gomes, M.E., Malcata, F.X., Technological optimization of manufacture of probiotic whey cheese matrices (2011) J. Food Sci., 76, pp. E203-E211 | |
dc.description | Madureira, A.R., Pintado, A.I., Gomes, A.M., Pintado, M.E., Malcata, F.X., Protective effect of whey cheese matrix on probiotic strains exposed to simulated gastrointestinal conditions (2011) Lebenson. Wiss. Technol., 44, pp. 75-81 | |
dc.description | Madureira, A.R., Pintado, A.I., Gomes, A.M., Pintado, M.E., Malcata, F.X., Rheological, textural and microstructural features of probiotic whey cheeses (2011) Lebenson. Wiss. Technol., 44, pp. 75-81 | |
dc.description | Martarelli, D., Verdenelli, M.C., Scuri, S., Cocchioni, M., Silvi, S., Cecchini, C., Pompei, P., Effect of a probiotic intake on oxidant and antioxidant parameters in plasma of athletes during intense exercise training (2011) Curr. Microbiol., 62, pp. 1689-1696 | |
dc.description | McCarthy, D.A., Dale, M.M., The leucocytosis of exercise. A review and model (1988) Sports Med., 6, pp. 333-363 | |
dc.description | Medici, M., Vinderola, C.G., Perdigón, G., Gut mucosal immunomodulation by probiotic fresh cheese (2004) Int. Dairy J., 14, pp. 611-618 | |
dc.description | Minervini, F., Siragusa, S., Faccia, M., Dal Bello, F., Gobbetti, M., De Angelis, M., Manufacture of Fior di Latte cheese by incorporation of probiotic lactobacilli (2012) J. Dairy Sci., 95, pp. 508-520 | |
dc.description | Minocha, A., Probiotics for preventive health (2009) Nutr. Clin. Pract., 24, pp. 227-241 | |
dc.description | Modzelewska-Kapituła, M., Kobukowski, J.A.N., Kłebukowska, L., The influence of feeding diets containing white cheese, produced with prebiotics and the potentially probiotic Lactobacillus plantarum strain, on the gastrointestinal microflora of rats (2010) Czech J. Food Sci., 28, pp. 139-145 | |
dc.description | Nichols, A.W., Probiotics and athletic performance: A systematic review (2007) Curr. Sports Med. Rep., 6, pp. 269-273 | |
dc.description | Ogué-Bon, E., Khoo, C., Hoyles, L., McCartney, A.L., Gibson, G.R., Rastall, R.A., In vitro fermentation of rice bran combined with Lactobacillus acidophilus 14 or Bifidobacterium longum 05 by the canine faecal microbiota (2011) FEMS Microbiol. Ecol., 75, pp. 365-376 | |
dc.description | Pedersen, B.K., Hoffman-Goetz, L., Exercise and the immune system: Regulation, integration, and adaptation (2000) Physiol. Rev., 80, pp. 1055-1081 | |
dc.description | Pflanzer Junior, S.B., Cruz, A.G., Sant'ana, A.S., Moura, M.R.L., Carvalho, L.M.J., Silva, R., Food safety knowledge of cheese consumers (2009) J. Food Sci., 94, pp. 28-30 | |
dc.description | Pregliasco, F., Anselmi, G., Fonte, L., Giussani, F., Schieppati, S., Soletti, L., A new chance of preventing winter diseases by the administration of synbiotic formulations (2008) J. Clin. Gastroenterol., 42 (SUPPL. 3 PART. 2), pp. S224-S233 | |
dc.description | Pyne, D.B., Gleeson, M., Effects of intensive exercise training on immunity in athletes (1998) Int. J. Sports. Med., 19 (SUPPL. 3), pp. S183-S191. , discussion S191-184 | |
dc.description | Pyne, D.B., McDonald, W.A., Gleeson, M., Flanagan, A., Clancy, R.L., Fricker, P.A., Mucosal immunity, respiratory illness, and competitive performance in elite swimmers (2001) Med. Sci. Sports Exerc., 33, pp. 348-353 | |
dc.description | Ross, R.P., Fitzgerald, G., Collins, K., Stanton, C., Cheese delivering biocultures: Probiotic cheese (2002) Aust. J. Dairy Technol., 57, pp. 71-78 | |
dc.description | Rowbottom, D.G., Green, K.J., Acute exercise effects on the immune system (2000) Med. Sci. Sports Exerc., 32 (SUPPL.), pp. S396-S405 | |
dc.description | Saad, S.M.I., Cruz, A.G., Faria, J.A.F., (2011) Probióticos e Prebióticos em Alimentos: Fundamentos e Aplicações Tecnológicas, , Varela, São Paulo, Brazil | |
dc.description | Savard, P., Lamarche, B., Paradis, M.-E., Thiboutot, H., Laurin, E., Roy, D., Impact of Bifidobacterium animalis ssp. lactis BB 12 and Lactobacillus acidophilus LA 5-containing yoghurt, on fecal bacterial counts of healthy adults (2011) Int. J. Food Microbiol., 149, pp. 50-57 | |
dc.description | Saxelin, M., Korpela, R., Mayra-Makinen, A., Introduction: Classifying functional dairy products (2003) Functional Dairy Products, pp. 1-16. , CRC Press, Boca Raton, FL, T. Mattila-Sandholm, M. Saarela (Eds.) | |
dc.description | Senchina, D.S., Effects of regular exercise on the aging immune system: A review (2009) Clin. J. Sport Med., 19, pp. 439-440 | |
dc.description | Souza, C.H.B., Saad, S.M.I., Viability of Lactobacillus acidophilus La-5 added solely or in co-culture with a yoghurt starter culture and implications on physico-chemical and related properties of Minas fresh cheese during storage (2009) Lebenson. Wiss. Technol., 42, pp. 633-640 | |
dc.description | Souza, T.B., Cruz, A.G., Moura, M.R.L., Vieira, A.C.M., Sant'Ana, A.S., Microscopic quality indicators of Minas frescal cheese (2008) Food Contr., 19, pp. 71-75 | |
dc.description | Steel, J.M., Steel, C.M., Johnstone, F.D., Leukocytosis induced by exercise (1987) Br. Med. J. (Clin. Res. Ed.), 295, pp. 1135-1136 | |
dc.description | Steensberg, A., The role of IL-6 in exercise-induced immune changes and metabolism (2003) Exerc. Immunol. Rev., 9, pp. 40-47 | |
dc.description | Steensberg, A., van Hall, G., Osada, T., Sacchetti, M., Saltin, B., Klarlund Pedersen, B., Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6 (2000) J. Physiol., 529, pp. 237-242 | |
dc.description | Todorov, S.D., Furtado, D.N., Saad, S.M.I., Franco, B.D.G.M., Bacteriocin production and resistance to drugs are advantageous features for Lactobacillus acidophilus La-14, a potential probiotic strain (2011) New Microbiol., 34, pp. 357-370 | |
dc.description | West, N.P., Pyne, D.B., Cripps, A.W., Hopkins, W.G., Eskesen, D.C., Jairath, A., Christophersen, C.T., Fricker, P.A., Lactobacillus fermentum (PCC ®) supplementation and gastrointestinal and respiratory-tract illness symptoms: A randomised control trial in athletes (2011) Nutr. J., 10, p. 30 | |
dc.description | West, N.P., Pyne, D.B., Peake, J.M., Cripps, A.W., Probiotics, immunity and exercise: A review (2009) Exerc. Immunol. Rev., 15, pp. 107-126 | |
dc.description | White, J.A., Hart, R.J., Fry, J.C., An evaluation of the Waters Pico-Tag system for the amino acid analysis of food materials (1986) J. Automat. Chem., 8, pp. 170-177 | |
dc.description | Woods, J.A., Vieira, V.J., Keylock, K.T., Exercise, inflammation, and innate immunity (2009) Immunol. Allergy Clin. North Am., 29, pp. 381-393 | |
dc.description | Zahorec, R., Ratio of neutrophil to lymphocyte counts-Rapid and simple parameter of systemic inflammation and stress in critically ill (2001) Bratisl. Lek Listy (Tlacene Vyd), 102, pp. 5-14 | |
dc.language | en | |
dc.publisher | | |
dc.relation | Journal of Dairy Science | |
dc.rights | aberto | |
dc.source | Scopus | |
dc.title | Probiotic Cheese Attenuates Exercise-induced Immune Suppression In Wistar Rats | |
dc.type | Artículos de revistas | |