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Mostrando ítems 21-30 de 40
Identificação de genes de predisposição ao desenvolvimento de câncer de tiroide familial não medular por análise de dados de exoma
(Universidade Federal de São Paulo, 2022)
O câncer de tiroide familial pode ser classificado em medular (CMT), associado a Neoplasia Endócrina Múltipla do tipo 2 (MEN2); ou em carcinoma familial não-medular da tiroide (FNMTC).
O FNMTC constitui de 3 a 9% de ...
Genomic and Transcriptomic Tumor Heterogeneity in Bilateral Retinoblastoma
(American Medical Association, 2020-05)
Importance: Comprehensive understanding of the genomic and gene-expression differences between retinoblastoma tumors from patients with bilateral disease may help to characterize risk and optimize treatment according to ...
Unraveling the oral cancer lncRNAome: Identification of novel lncRNAs associated with malignant progression and HPV infection
(Elsevier Science, 2016-08)
SummaryObjectives The role of long non-coding RNA (lncRNA) expression in human head and neck squamous cell carcinoma (HNSCC) is still poorly understood. In this study, we aimed at establishing the onco-lncRNAome profiling ...
Protocolo de assistência ventilatória mecânica em pacientes com neoplasias oncohematológicas e insuficiência respiratória aguda
(Universidade Federal de Minas GeraisUFMG, 2018-08-28)
Introduction: Acute respiratory failure (ARF) is one of the main causes of transference of oncohaematological patients to intensive care units (ICUs). As in other patient groups, noninvasive mechanical ventilation (NIMV) ...
D-propranolol impairs egfr trafficking and destabilizes mutant p53 counteracting akt signaling and tumor malignancy
(2021-07-02)
Cancer therapy may be improved by the simultaneous interference of two or more onco-genic pathways contributing to tumor progression and aggressiveness, such as EGFR and p53. Tumor cells expressing gain-of-function (GOF) ...
Estudio del potencial oncolítico del aislamiento rotaviral humano Wt1-5 en adenocarcinoma gástrico
(Universidad Nacional de ColombiaBogotá - Ciencias - Doctorado en BiotecnologíaFacultad de CienciasBogotá,ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2022-07-01)
A pesar de los avances en la investigación en ciencias biomédicas, el cáncer gástrico sigue siendo una de las principales causas de morbilidad y mortalidad en el mundo debido a la limitada eficacia de las terapias ...
Aberrant fucosylation enables breast cancer clusterin to interact with dendritic cell-specific ICAM-grabbing non-integrin (DC-SIGN)
(Taylor & Francis, 2019-09-24)
Clusterin is a glycoprotein able to mediate different physiological functions such as control of complement activation, promotion of unfolded protein clearance and modulation of cell survival. Clusterin is overexpressed ...