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Human and animal models for translational research on neurodegeneration: Challenges and opportunities from South America
(Frontiers Media S.A., 2018-04)
Facing the alarming growth of dementia and neurodegenerative conditions has become a critical priority across the globe (Alzheimer´s Disease International, 2009;Lancet, 2015;Shah et al., 2016;Parra et al., 2018). ...
Bacillus Subtilis Delays Neurodegeneration and Behavioral Impairment in the Alzheimer's Disease Model Caenorhabditis Elegans
(IOS Press, 2019-12)
Multiple causes, apart from genetic inheritance, predispose to the production and aggregation of amyloid-β (Aβ) peptide and Alzheimer's disease (AD) development in the older population. There is currently no therapy or ...
Robust automated computational approach for classifying frontotemporal neurodegeneration: Multimodal/multicenter neuroimaging
(Elsevier, 2019-09)
Introduction: Timely diagnosis of behavioral variant frontotemporal dementia (bvFTD) remains challenging because it depends on clinical expertise and potentially ambiguous diagnostic guidelines. Recent recommendations ...
Editorial: Human and animal models for translational research on neurodegeneration: Challenges and opportunities from South America
(Frontiers Media S.A., 2018-04)
Facing the alarming growth of dementia and neurodegenerative conditions has become a critical priority across the globe (Alzheimer’s Disease International, 2009; Lancet, 2015; Shah et al., 2016; Parra et al., 2018). ...
Explicit and implicit monitoring in neurodegeneration and stroke
(Nature Publishing Group, 2019-10)
Monitoring is a complex multidimensional neurocognitive phenomenon. Patients with fronto-insular stroke (FIS), behavioural variant frontotemporal dementia (bvFTD) and Alzheimer?s disease (AD) show a lack of self-awareness, ...
Efectos del envejecimiento y la neurodegeneración sobre la plasticidad neuronal en el hipocampoEffects of ageing and neurodegeneration on neuronal plasticity in the hippocampus
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2011)
Oxidative stress in neurodegenerative diseases: Mechanisms and therapeutic perspectives
(Hindawi Publishing Corporation, 2011)
The incidence and prevalence of neurodegenerative diseases (ND) increase with life expectancy. This paper reviews the role of oxidative stress (OS) in ND and pharmacological attempts to fight against reactive oxygen species ...
Axonal degeneration during aging and its functional role in neurodegenerative disorders
(Frontiers Media S.A., 2017)
Aging constitutes the main risk factor for the development of neurodegenerative diseases. This represents a major health issue worldwide that is only expected to escalate due to the ever-increasing life expectancy of the ...
Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
(2020)
Hereditary mutations in polynucleotide kinasephosphatase
(PNKP) result in a spectrum of neurological
pathologies ranging from neurodevelopmental
dysfunction in microcephaly with early onset
seizures (MCSZ) to ...