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Mostrando ítems 491-500 de 1395
Increases of kinin B-1 and B-2 receptors binding sites after brain infusion of amyloid-beta 1-40 peptide in rats
(Elsevier B.V., 2008-12-01)
Although numerous inflammation pathways have been implicated in Alzheimer's disease, the involvement of the kallikrein-kinin system is still under investigation. We anatomically localized and quantified the density of kinin ...
Transcriptional analysis of blood lymphocytes and skin fibroblasts, keratinocytes, and endothelial cells as a potential biomarker for alzheimer’s disease
(Journal of Alzheimer's Disease, 2018)
Cambios exofocales en la isquemia cerebral focal experimental : una visión experimental y su correlato clínico.
(2012-11-30)
Introducción: El cerebro es un órgano extraordinariamente dinámico, su fisiología es sorprendente especialmente por la
respuesta concertada del tejido nervioso en su conjunto ante situaciones patológicas. Estas respuestas ...
Neurodegeneração promovida pelo heme em modelo de injeção intracerebral
(Universidade Federal do Rio de JaneiroBrasilInstituto de Microbiologia Paulo de GóesUFRJ, 2022)
Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease
(NATL ACAD SCIENCES, 2008-11-25)
Dopaminergic cell death in the substantia nigra (SN) is central to
Parkinson’s disease (PD), but the neurodegenerative mechanisms
have not been completely elucidated. Iron accumulation in dopaminergic
and glial cells ...
Illness duration and total brain gray matter in bipolar disorder: Evidence for neurodegeneration?
(ELSEVIER SCIENCE BV, 2008)
Previous studies have suggested that bipolar disorder (BD) is associated with alterations in neuronal plasticity, but the effects of the progression of illness on brain anatomy have been poorly investigated. We studied the ...
Exercise reduces inhibitory neuroactivity and protects myenteric neurons from age-related neurodegeneration
(ELSEVIER SCIENCE BV, 2008)
The practice of regular exercise is indicated to prevent some motility disturbances in the gastrointestinal tract, such as constipation, during aging. The motility alterations are intimately linked with its innervations. ...
Microglial cells are involved in the susceptibility of NADPH oxidase knockout mice to 6-hydroxy-dopamine-induced neurodegeneration
(Public Library of ScienceSan Francisco, 2013)
We explored the impact of Nox-2 in modulating inflammatory-mediated microglial responses in the 6-hydroxydopamine (6-OHDA)-induced Parkinson’s disease (PD) model. Nox1 and Nox2 gene expression were found to increase in ...