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Astrocytic and microglial response and histopathological changes in the brain of horses with experimental chronic Trypanosoma evansi infection
(Instituto de Medicina Tropical, 2014)
Α7 nicotinic acetylcholine receptor signaling modulates ovine fetal brain astrocytes transcriptome in response to endotoxin
(Frontiers Media S.A., 2019-05)
Neuroinflammation in utero may result in lifelong neurological disabilities. Astrocytes play a pivotal role in this process, but the mechanisms are poorly understood. No early postnatal treatment strategies exist to enhance ...
Prenatal stress increases the expression of proinflammatory cytokines and exacerbates the inflammatory response to LPS in the hippocampal formation of adult male mice
(Academic Press Inc Elsevier Science, 2013-02)
Early life experiences, such as prenatal stress, may result in permanent alterations in the function of the nervous and immune systems. In this study we have assessed whether prenatal stress affects the inflammatory response ...
Schizophrenic patients hiPSC-derived astrocytes impair synaptic material engulfment by induced microglial-like cells (iMGs)
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2022-08-23)
A esquizofrenia (SCZ) é uma desordem psiquiátrica, cujas causas estão associadas à interação entre fatores genéticos e ambientais. Indivíduos com esquizofrenia apresentam sintomas classificados como positivos (delírios, ...
Papel de NLRP3 no controle da infecção por Trypanosoma cruzi em células gliais
(Universidade Federal de São Paulo, 2016-08-12)
Trypanosoma cruzi (T. cruzi) is the etiologic agent of Chagas disease. Although T. cruzi is mainly described by its ability to cause heart and gut pathologies, imunocompromised chagasic individuals frequently present ...