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Estudo da analgesia induzida por administração de antagonista de receptores NMDA – Comparação entre a administração central (intratecal) e periférica (gânglio da raiz dorsal) em modelos de dor e hiperalgesia em ratosStudy of analgesia induced by administration of NMDA receptor antagonist - Comparison between central (intrathecal) and peripheral (dorsal root ganglion) administration in pain and hyperalgesia models in rats
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Ciências da Saúde, 2019)
A decision process for drug discovery in retinoblastoma
(Springer, 2020-11)
Intraocular retinoblastoma treatment has changed radically over the last decade, leading to a notable improvement in ocular survival. However, eyes that relapse remain difficult to treat, as few alternative active drugs ...
Antinociceptive effect and interaction of uncompetitive and competitive NMDA receptor antagonists upon capsaicin and paw pressure testing in normal and monoarthritic rats
(2008)
We assessed whether intrathecal administration of the uncompetitive and competitive NMDA receptor antagonists ketamine and (±)CPP, respectively, could produce differential modulation on chemical and mechanical nociception ...
Previous administration of naltrexone did not change synergism between paracetamol and tramadol in mice
(2012)
In the treatment of acute and chronic pain the most frequently used drugs are nonsteroidal anti-inflammatory drugs (NSAIDs), e.g., paracetamol; opioids, e.g., tramadol, and a group of drugs called coanalgesics or adjuvants ...
A decision process for drug discovery in retinoblastoma
(Springer, 2020-11)
Intraocular retinoblastoma treatment has changed radically over the last decade, leading to a notable improvement in ocular survival. However, eyes that relapse remain difficult to treat, as few alternative active drugs ...
Antibióticos intratecales en pacientes adultos
(Sociedad Chilena de Infectología, 2003)
Estudo do potencial analgésico e antiinflamatório do 3-(4-fluorfenil)-5-trifluormetil-1h-1-tosilpirazol em modelos de dor em camundongos
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2009-12-18)
Pain is the most common complaint in the medical field and the identification of compounds that can effectively treat painful states without induction of side-effects remains a major challenge in biomedical research. The ...
Efeitos da administração subaracnoidea em punção única, de cetamina S(+) a 5%, sem conservantes, sobre a medula espinal e as meninges de coelhosEffects of ketamine S(+) 5% preservative free, administered by the intrathecal route in single pincture, determines on the spinal cord and meninges of rabbits
(Universidade Estadual Paulista (Unesp), 2015)
Avaliação da atividade antinociceptiva espinal da toxina Ph1 isolada dp veneno da Phoneutria nigriventer em rodedores
(Universidade Federal de Minas GeraisUFMG, 2008-12-03)
Calcium influx through voltage sensitive calcium channels (VSCCs) plays an important role on the nociceptive transmission in the dorsal horn of the spinal cord. The intrathecal administration of VSCCs blockers, such as ...