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Obesity influences the proteome of periodontal ligament tissues following periodontitis induction in rats
(2022-01-01)
Background and Objectives: Many studies have been conducted to better understand the molecular mechanism involved with periodontitis progression. There has been growing interest in the potential impact of obesity on ...
Myeloperoxidase as inflammatory marker of periodontal disease: Experimental study in rats
(2009-11-09)
Rationale: Previous studies have used myeloperoxidase (MPO) as an inflammatory marker to estimate the accumulation of neutrophils in inflamed regions. Objective: The aim of this experimental study was to quantify the levels ...
Host responses induced by different animal models of periodontal disease: a literature review
(2012)
Periodontitis is an infectious disease characterized by chronic inflammation of the periodontium, and it is mediated and modulated by the host immune system. In the presence of microorganisms or other antigens, immune cells ...
Influence of Parstatin on Experimental Periodontal Disease and Repair in Rats
(Amer Acad Periodontology, 2014-09-01)
Background: Parstatin is a 41-amino acid peptide, formed by proteolytic cleavage on activation of the protease activated receptor-1, with antiangiogenic properties. The purpose of this study is to evaluate the influence ...
Influence of immunosuppression on the progression of experimental periodontitis and on healthy periodontal tissue: A rat in vivo study
(2021-01-01)
Background. The potent anti-inflammatory and immunosuppressive properties of glucocorticoids (GCs) might influence the progression of some disorders, such as periodontitis. Hence, this study aimed to investigate the influence ...
Regulation of tyrosine hydroxylase in periodontal fibroblasts and tissues by obesity-associated stimuli
(2019-03-05)
Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the synthesis of catecholamines and has been connected to aggravated progression of periodontal disease under chronic stress. Obesity is known to increase the ...
Antiplatelet drugs reduce the immunoinflammatory response in a rat model of periodontal disease
(Wiley-Blackwell, 2014-12-01)
Background and ObjectiveAfter activation, platelets express mediators that modulate inflammation. We hypothesized that drug-induced platelet inactivation may interfere in the inflammatory process in experimental periodontal ...
Effect of induced diabetes mellitus on alveolar bone loss after 30 days of ligature-induced periodontal disease
(2009-04-01)
Several studies have shown that diabetics are more susceptible to the development of severe periodontal disease. Currently, the use of animal models can be considered a feasible alternative in radiographic assessments of ...
Effect of induced diabetes mellitus on alveolar bone loss after 30 days of ligature-induced periodontal disease
(2009-04-01)
Several studies have shown that diabetics are more susceptible to the development of severe periodontal disease. Currently, the use of animal models can be considered a feasible alternative in radiographic assessments of ...