Buscar
Mostrando ítems 21-30 de 225
C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists
(ELSEVIER, 2006)
Neuronal nicotinic acetylcholine receptors subserve predominantly modulatory roles in the brain, making them attractive therapeutic targets. Natural products provide key leads in the quest for nicotinic receptor subtype-selective ...
Urodilatin regulates renal dopamine metabolism
(Società Italiana di Nefrologia, 2013-05)
Sodium and water transport across renal proximal tubules is regulated by diverse hormones such as dopamine and urodilatin. We have previously reported that urodilatin stimulates extraneuronal dopamine uptake in external ...
Dopamine-induced apoptosis of lactotropes is mediated by the short isoform of D2 receptor
(Public Library of Science, 2011-03)
Dopamine, through D2 receptor (D2R), is the major regulator of lactotrope function in the anterior pituitary gland. Both D2R isoforms, long (D2L) and short (D2S), are expressed in lactotropes. Although both isoforms can ...
Dopamine receptor D2 maps to bovine chromosome 15
(Blackwell Science, 1999-10-01)
Disruption of the dopamine D2 receptor impairs insulin secretion and causes glucose intolerance
(Oxford University Press, 2010-04)
The relationship between antidopaminergic drugs and glucose has not been extensively studied, even though chronic neuroleptic treatment causes hyperinsulinemia in normal subjects or is associated with diabetes in psychiatric ...
Presencia de los alelos DRD4/7R y DAT1/10R en miembros de familias chilenas con síndrome de déficit atencional con hiperactividad
(Sociedad Médica de Santiago, 2004)
Hyperactivity induced by the dopamine D2/D3 receptor agonist quinpirole is attenuated by inhibitors of endocannabinoid degradation in mice
(Cambridge University Press, 2013-04)
The present study was designed to investigate the effect of pharmacological inhibition of endocannabinoid degradation on behavioural actions of the dopamine D2/D3 receptor agonist quinpirole in male C57Bl/6J mice. In ...
Time course of deficits in open field behavior after unilateral neostriatal 6-hydroxydopamine lesions
(2002)
In this study, the degree and time course of deficits in open field behavior was analyzed in male Wistar rats (aged 1 year) which had received unilateral neostriatal lesions with 6-OHDA. The post-mortem neurochemical ...