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Striated muscle involvement in experimental oral infection by herpes simplex virus type 1
(Wiley Blackwell Publishing, Inc, 2013-07)
Herpes simplex virus type 1 is one of the most frequent causes of oral infection in humans, especially during early childhood. Several experimental models have been developed to study the pathogenesis of this virus but all ...
Glial cell-elicited activation of brain microvasculature in response to brucella abortus infection requires asc inflammasome-dependent IL-1b production
(American Association of Immunologists, 2016-05)
Blood-brain barrier activation and/or dysfunction are a common feature of human neurobrucellosis, but the underlying pathogenic mechanisms are largely unknown. In this article, we describe an immune mechanism for inflammatory ...
Antibody banding patterns of the enzyme-linked immunoelectrotransfer blot and brain imaging findings in patients with Neurocysticercosis
(Oxford University Press, 2018)
Background: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections ...
Porcine model of neurocysticercosis by intracarotid injection of Taenia solium oncospheres: Dose assessment, infection outcomes and serological responses
(Public Library of Science, 2022)
BACKGROUND: Neurocysticercosis (NCC) is the infection of the human central nervous system (CNS) by Taenia solium larvae that cause significant neurological morbidity. Studies on NCC pathophysiology, host-parasite interactions ...
Experimental brain infection with cysticercosis in sheep
(Instituto Nacional de Salud, 2022)
Objective. To explore the feasibility of developing a sheep model of neurocysticercosis (NCC) by intracranial infection with T. solium oncospheres. Materials and methods. We carried out an experimental infection model of ...
Brucella abortus-Stimulated Platelets Activate Brain Microvascular Endothelial Cells Increasing Cell Transmigration through the Erk1/2 Pathway
(Multidisciplinary Digital Publishing Institute, 2020-08)
Central nervous system invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. A common feature associated with this pathology is blood–brain barrier (BBB) activation. However, ...
Central Nervous System Targets and Routes for SARS-CoV-2: Current Views and New Hypotheses
(American Chemical Society Inc, 2020-09)
As the coronavirus disease 2019 (COVID-19) pandemic unfolds, neurological signs and symptoms reflect the involvement of targets beyond the primary lung effects. The etiological agent of COVID-19, the severe acute respiratory ...
Inflammation Caused by Praziquantel Treatment Depends on the Location of the Taenia solium Cysticercus in Porcine Neurocysticercosis
(Public Library of Science, 2015)
BACKGROUND: Neurocysticercosis (NCC), infection of the central nervous system by Taenia solium cysticerci, is a pleomorphic disease. Inflammation around cysticerci is the major cause of disease but is variably present. ...
Changes in inflammatory gene expression in brain tissue adjacent and distant to a viable cyst in a rat model for neurocysticercosis
(Public Library of Science, 2021)
BACKGROUND: The parasite Taenia solium causes neurocysticercosis (NCC) in humans and is a common cause of adult-onset epilepsy in the developing world. Hippocampal atrophy, which occurs far from the cyst, is an emerging ...
THE INFLUENCE OF SALT INTAKE ON THE COURSE OF EXPERIMENTAL TOXOPLASMOSIS IN OUTBRED OR INBRED MOUSE STRAINS
(Universidade Federal de Goiás, 2018)