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Análisis histopatológico de tejido cardiaco en ratones experimentalmente infectados con Trypanosoma cruzi
(Universidad de Chile, 2013)
Ratones de la cepa ACA fueron experimentalmente infectados con 2.000 trypomastigotes sanguíneos de la cepa Tulahuén o de la cepa Munantá de Trypanosoma cruzi para evaluar prepatencia, niveles de parasitemia, mortalidad ...
Evaluación de calreticulina recombinante humana versus parasitaria de Trypanosoma cruzi sobre la regeneración ósea en conejos
(Universidad de Chile, 2013)
En cirugía ortopédica, el uso de factores tróficos que favorezcan la formación de tejido de granulación y eviten o retrasen la formación de nuevo hueso es deseable en resoluciones quirúrgicas de ciertas patologías en ...
Enfermedad de Chagas crónica. Ausencia de Triatoma infestans intradomiciliario y persistencia de Trypanosoma cruzi circula
(2004)
In 1999 Chile declare no vectorial transmission of Chagas disease. On the other hand, the
development of dwelling policy which include endemic rural zones, have obtained important advances
in human groups with height ...
Influencia de la dosis de inóculo inicial en la infección con Trypanosoma cruzi en un modelo murino, según el sexo
(Universidad de Chile, 2004)
Se infectaron ratones de la cepa ACA, machos y hembras, con 200 y 2000 trypomastigotes sanguíneos del clon Dm28c de Trypanosoma cruzi. Todos los animales se comportaron como susceptibles a la infección, independientemente ...
DHEA and testosterone therapies in Trypanosoma cruzi-infected rats are associated with thymic changes
(ELSEVIER SCI LTD, 2010)
The ability of the gonadal hormones to influence diverse immunological functions during the course of several infections has been extensively studied in the latest decades. Testosterone has a suppressive effect on immune ...
ORGANIZATION and EXPRESSION of the GENE ENCODING AN IMMUNODOMINANT REPETITIVE ANTIGEN ASSOCIATED TO the CYTOSKELETON of TRYPANOSOMA-CRUZI
(Elsevier B.V., 1995-04-01)
We have studied the genomic organization and expression of the gene encoding a high molecular mass (300 kDa) repetitive antigen associated with the cytoskeleton of Trypanosoma cruzi. Protease digestion of the native protein, ...
Phosphatidylinositol-specific phospholipase C (PI-PLC) cleavage of GPI-anchored surface molecules of Trypanosoma cruzi triggers in vitro morphological reorganization of trypomastigotes
(Soc Protozoologists, 2001-01-01)
Trypanosoma cruzi trypomastigotes treated with phosphatidylinositol-specific phospholipase C (PI-PLC) in vitro are rapidly induced to differentiate into round forms. Using confocal microscopy, we were able to show that ...
Optimization of physicochemical properties is a strategy to improve drug-likeness associated with activity: Novel active and selective compounds against Trypanosoma cruzi
(Elsevier, 2022)
Trypanosoma cruzi is the causing agent of Chagas disease, a parasitic infection without efficient treatment for chronic patients. Despite the efforts, no new drugs have been approved for this disease in the last 60 years. ...
Pharmacokinetic and tissue distribution of benznidazole after oral administration in mice
(American Society for Microbiology, 2018)