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Hydrogen peroxide-mediated oxidative stress induces inflammasome activation in term human placental explants
(2018-10-01)
Background: The placenta is a multifunctional organ that can suffer with imbalances between pro- and antioxidant molecules, contributing for inflammatory imbalance. The inflammation generated by oxidative stress may induce ...
Exercise during transition from compensated left ventricular hypertrophy to heart failure in aortic stenosis rats
(2019-02-01)
We evaluated the influence of aerobic exercise on cardiac remodelling during the transition from compensated left ventricular (LV) hypertrophy to clinical heart failure in aortic stenosis (AS) rats. Eighteen weeks after ...
New insights into cadmium stressful-conditions: Role of ethylene on selenium-mediated antioxidant enzymes
(2019-12-30)
Cadmium (Cd) contamination has generated an environmental problem worldwide, leading to harmful effects on human health and damages to plant metabolism. Selenium (Se) is non essential for plants, however it can improve ...
Tannic acid, a promising anti-photoaging agent: Evidences of its antioxidant and anti-wrinkle potentials, and its ability to prevent photodamage and MMP-1 expression in L929 fibroblasts exposed to UVB
(2020-11-20)
Chronic and unprotect UV exposure leads to skin oxidative stress, following accumulation of damaged cellular components and downstream activation of specific signaling pathways, culminating in premature skin aging (photoaging). ...
A phytotoxicity assessment of the efficiency 2,4-D degradation by different oxidative processes
(2020-07-15)
Highly stable compounds such as dichlorophenoxyacetic acid (2,4-D), which are present in the commercial herbicide Tordon®, are difficult to degrade. Therefore, the objective of this work was to degrade 2,4-D present in ...
Influence of apocynin on cardiac remodeling in rats with streptozotocin-induced diabetes mellitus
(2018-01-17)
Background: Increased reactive oxygen species (ROS) generation in diabetes mellitus (DM) is an important mechanism leading to diabetic cardiomyopathy. Apocynin, a drug isolated from the herb Picrorhiza kurroa, is considered ...
Nonpregnant and pregnant adult female rats affected by maternal diabetes environment
(Taylor & Francis Inc, 2022-09-14)
Maternal diabetes-mediated fetal programming is widely discussed, however, it is important to define the extent to which intrauterine hyperglycemia interferes with the health of female pups, along with determining whether ...
Effects of chlorpyrifos on enzymatic systems of Cydia pomonella (Lepidoptera: Tortricidae) adults
(Wiley, 2017-06)
The control program of codling moth (Cydia pomonella L.) in the Río Negro and Neuquén Valley is intended to neonate larvae. However, adults may be subjected to sublethal pesticide concentrations generating stress which ...
Expressing the sunflower transcription factor HaHB11 in maize improves waterlogging and defoliation tolerance
(Oxford University Press, 2022-05)
The sunflower (Helianthus annuus) transcription factor HaHB11 (H. annuus Homeobox 11) belongs to the homeodomain-leucine zipper family and confers improved yield to maize (Zea mays) hybrids (HiII × B73) and lines. Here we ...
Knockdown of amyloid precursor protein normalizes cholinergic function in a cell line derived from the cerebral cortex of a trisomy 16 mouse: An animal model of Down syndrome
(WILEY-LISS, 2006-11-01)
We have generated immortal neuronal cell lines from normal and trisomy 16 (Ts16) mice, a model for Down syndrome (DS). Ts16 lines overexpress DS-related genes (App, amyloid precursor protein; Sod1, Cu/Zn superoxide dismutase) ...