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Endometrial expression of key genes related to fertility in repeat breeder and non-repeat breeder cows
(Wiley Blackwell Publishing, Inc, 2020-11)
The aim of the present study was to compare the endometrial gene expression of epidermal growth factor receptor (EGFR), nodal growth differentiation factor (NODAL), prostaglandin-endoperoxide synthase 2 (PTGS2), oestrogen ...
Virtual screening of plants extracts with anti-chagasic activity guided by Omics data
(Asociación Argentina de Bioinformática y Biología Computacional, 2021)
Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and their treatment consists in the use of two nitro heterocyclic compounds that both present high toxicity and low effectiveness during the chronic ...
Transcriptomic analysis of differential gene expression reveals an increase in COX2 levels during in vitro canine herpesvirus infection
(Univ Federal Santa Maria, 2018-01-01)
Canine herpesvirus (CaHV-1) affects canids worldwide, causing death in neonates and immunosuppressed hosts. Acute infection by CaHV-1 can cause reproductive. respiratory, and neurological problems in adult animals. Kral ...
Transcriptomics of the fetal hypothalamic response to brachiocephalic occlusion and estradiol treatment
(American Physiological Society, 2014-05)
Estradiol (E2) is a well-known modulator of fetal neuroendocrine activity and has been proposed as a critical endocrine signal readying the fetus for birth and postnatal life. To investigate the modulatory role of E2 on ...
Síntese e modelagem molecular do novo derivado indolinônico como candidato a antiinflamatório COX-2 seletivo
(2007-12-01)
Anti-inflammatory drugs are known to be the most widely-marketed drugs in the world, despite their serious side effects, mainly on the gastrointestinal tract. Thus, there are constant efforts to discover new prototypes ...
Síntese e modelagem molecular do novo derivado indolinônico como candidato a antiinflamatório COX-2 seletivo
(2007-12-01)
Anti-inflammatory drugs are known to be the most widely-marketed drugs in the world, despite their serious side effects, mainly on the gastrointestinal tract. Thus, there are constant efforts to discover new prototypes ...