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Mostrando ítems 11-20 de 40
High-resolution structures of mutants of residues that affectaccess to the ligand-binding cavity of human lipocalin-typeprostaglandin D synthase
(Wiley Blackwell Publishing, Inc, 2014-05)
Lipocalin-type prostaglandin D synthase (L-PGDS) catalyzes the isomerization of the 9,11-endoperoxide group of PGH2 (prostaglandin H2) to produce PGD2 (prostaglandin D2) with 9-hydroxy and 11-keto groups. The product of ...
Peri-ovulatory endocrine regulation of the prostanoid pathways in the bovine uterus at early dioestrus
(Csiro Publishing, 2017-01-01)
We hypothesised that different endocrine profiles associated with pre-ovulatory follicle (POF) size would impact on uterine prostanoid pathways and thereby modulate the histotroph composition. Beef cows (n=15 per group) ...
Estudo do mecanismo do nitrofeniletano na prostaglandina-endoperóxido sintase e relação estrutura-propriedade de nitroderivadosStudy of the mechanism of nitrophenylethane in prostaglandin-endoperoxide synthases and structureproperty relationship of nitro derivatives
(Universidade Federal do ParáBrasilInstituto de Ciências da SaúdeUFPAPrograma de Pós-Graduação em Ciências Farmacêuticas, 2014)
Exenatide and sitagliptin decrease interleukin 1β, matrix metalloproteinase 9, and nitric oxide synthase 2 gene expression but does not reduce alveolar bone loss in rats with periodontitis
(Journal of Periodontology, 2015)
New drugs for the treatment of diabetes, glucagon-like peptide-1 (GLP-1) receptor agonists and inhibitors of dipeptidyl peptidase-4 (DPP-4) have shown pleiotropic effects on bone metabolism and anti-inflammatory properties. ...
Temporal gene expression in the hippocampus and peripheral organs to endotoxin-induced systemic inflammatory response in caspase-1-deficient mice
Objectives: Caspase-1 (casp1), a key protease involved in the systemic inflammatory response syndrome (SIRS), controls the brain expression of a set of eight genes: Nos2 and Ptgs2 (nitric oxide synthase 2 and prostagland ...
Fibroblast growth factor 17 and bone morphogenetic protein 15 enhance cumulus expansion and improve quality of in vitro-produced embryos in cattle
(Elsevier B.V., 2015-08-01)
Bone morphogenetic protein 15 (BMP15) and members of the fibroblast growth factor (FGF) family are expressed by the oocyte and are involved in the control of cumulus cell function. We tested the hypothesis that FGF17, alone ...
Efecto del ácido linoléico sobre la producción de las prostaglandinas PGF2α y PGE2 en células endometriales
(Universidad de Córdoba, 2013)