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Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing
(Frontiers Research Foundation, 2019-10)
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. In T. cruzi the transport of polyamines is essential because this organism is unable to synthesize these compounds ...
Triggering doxorubicin release from responsive hydrogel films by polyamine uptake
(Royal Society of Chemistry, 2020-07-14)
Polyamines such as putrescine, spermidine and spermine are required in many inter- and intra-cellular processes. There is, however, evidence of anomalously high concentrations of these polyamines around cancer cells. ...
Vibrational study of polyamine copper(II) complexes. Infrared spectra and normal coordinate analysis of mono(diethylenetriamine)copper(II) complex ions
(1992)
The results of an investigation of the infrared spectra of mono(diethylenetriamine)copper(II) compounds are reported, with particular reference to the low-energy region. Most assignments are based on the available literature. ...
Polyamines are central molecules in nitrogen metabolism
(Research Trends, 2018-12)
Polyamines are central molecules in nitrogen metabolism
Polyamines and inhibitors used in successive culture media for in vitro rooting in Berberis buxifolia
(Royal Society of New Zealand, 2005-12)
Although Berberis buxifolia has been reported to propagate in vitro, rooting is difficult to achieve during subcultures, with reduced quantity and quality of roots, as is the case with many other woody species. Several ...
Endogenous and food-derived polyamines: determination by electrochemical sensing
(2018-09-01)
Polyamines (PAs) are involved in a variety of fundamental physio-pathologic processes. The concentration of these polycations in organs and tissues depends on their endogenous production and oxidation rates, and on their ...
Optimization of the analytical extraction of polyamines from milk
(Elsevier Science BvAmsterdamHolanda, 2011)
Polyamines prevent DFMO-mediated inhibition of angiogenesis
(Elsevier, 1994-04-24)
Tumor growth mainly depend on formation of new blood vessels. DFMO (α-difluoromethylornithine), an inhibitor of polyamine biosynthesis, inhibits tumor growth in many animal tumors. Our investigation was to evaluate the ...
Parasite Polyamines
(Bentham Science Publishers, 2018)
Defining novel plant polyamine oxidase subfamilies through molecular modeling and sequence analysis
(BioMed Central, 2019-01)
Background: The polyamine oxidases (PAOs) catabolize the oxidative deamination of the polyamines (PAs) spermine (Spm) and spermidine (Spd). Most of the phylogenetic studies performed to analyze the plant PAO family took ...