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Oxidative stress promotes doxorubicin-induced pgp and bcrp expression in colon cancer cells under hypoxic conditions.
(2017)
P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) are ATP binding cassette (ABC) transporters that are overexpressed in different drug-resistant cancer cell lines. In this study, we investigated whether ...
Plantas medicinales reportadas con reacciones adversas en Cuba: potenciales interacciones con fármacos de uso convencional
(2015)
Los productos herbales constituyen mezclas de principios activos, lo que conlleva a formulaciones químicamente complejas, que incrementan la posibilidad de interacciones con fármacos de uso convencional. Existen varios ...
Potential of bioremediation and PGP traits in streptomyces as strategies for bio-reclamation of salt-affected soils for agriculture
(Multidisciplinary Digital Publishing Institute, 2020-02-13)
Environmental limitations influence food production and distribution, adding up to global problems like world hunger. Conditions caused by climate change require global efforts to be improved, but others like soil degradation ...
P-Glycoprotein and Androgen Receptor Expression Reveals Independence of Canine Prostate Cancer from Androgen Hormone Stimulation
(2022-02-01)
Canine prostate cancer (PC) is an aggressive disease, and dogs can be considered comparative models for human PC. In recent years, canine PC has been shown to resemble human castrate-resistant prostate cancer. The influx ...
Increased delivery of chemotherapy to the vitreous by inhibition of the blood-retinal barrier
(Elsevier Science, 2017-10)
Treatment of retinoblastoma -a pediatric cancer of the developing retina- might benefit from strategies to inhibit the blood-retinal barrier (BRB). The potent anticancer agent topotecan is a substrate of efflux transporters ...
Contribution of skin immunohistochemistry in the evaluation of nerve fibers in diabetes mellitus type 2 (abstract). Thesis. Campinas, 2001.
(Assoc Arquivos De Neuro- PsiquiatriaSao Paulo SpBrasil, 2002)
Development of a highly specific ensemble of topological models for early identification of P-glycoprotein substrates
(John Wiley & Sons Ltd, 2011-06)
P-glycoprotein (Pgp) is an ATP-dependent efflux transporter protein associated with multidrug resistance in several diseases such as cancer, epilepsy and AIDS. It is preferentially expressed in organs and tissues that ...
Assessment of P-glycoprotein gene expression in adult stage of Haemonchus contortus in vivo exposed to ivermectin
(Elsevier Science, 2018-12)
The efflux transporter P-glycoprotein (P-gp) has been implicated in multidrug resistance of different nematode parasites affecting livestock species. Increased expression of P-gp in nematodes after their in vitro as well ...
P-glycoprotein activation by 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) in rat distal ileum: ex vivo and in vivo studies
(Academic Press Inc Elsevier Science, 2020-01)
In vitro studies showed that 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) increases P-glycoprotein (P-gp) expression and activity in Caco-2 cells, preventing xenobiotic toxicity. The present study aimed at ...