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Calpain translocation and activation as pharmacological targets during myocardial ischemia/reperfusion
(2010)
Calpains contribute to reperfusion-induced myocardial cell death. However, it remains controversial whether its activation occurs during ischemia or reperfusion. We investigated the regulation and time-course of calpain ...
Investigations on the new free radical scavenger polynitroxyl-albumin to prevent ischemia and reperfusion injury after orthotopic heart transplantation in the pig model
(Elsevier B.V., 2001-03-01)
Objective: Nitroxides have strong antioxidant capacity but their effectiveness is limited by their rapid intracellular inactivation. Poly nitroxyl-Albumin (PNA) is capable of regenerating inactivated nitroxide. We tested ...
High cholesterol diet effects on ischemia- reperfusion injury of the heart
(National Research Council Canada-NRC Research Press, 2012-09)
Ischemic heart disease is the leading cause of morbi-mortality in developed countries. Both ischemia-reperfusion injury and mechanisms of cardioprotection have been studied for more than 50 years. It is known that the ...
Signaling Pathways Involved in Myocardial Ischemia–Reperfusion Injury and Cardioprotection: A Systematic Review of Transcriptomic Studies in Sus scrofa
(MDPI. International Journal of Environmental Research and Public Health, 2023)
Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocyte recruitment
(Federation Amer Soc Exp Biol, 2000-10-01)
Potential Therapies to Protect the Aging Heart Against Ischemia/Reperfusion Injury
(Frontiers Media, 2021)
Despite important advances in the treatment of myocardial infarction that have significantly reduced mortality, there is still an unmet need to limit the infarct size after reperfusion injury in order to prevent the onset ...
Mechanisms Involved in Exercise-Induced Cardioprotection: A Systematic Review
(Sociedade Brasileira de Cardiologia - SBC, 2016)